Bronchogenic and Esophageal Cyst With Laryngeal Malformations in a Thoroughbred Foal

Abstract

This report documents an unusual case of congenital foregut cyst with dysphagia and stridor in a Thoroughbred foal. Histologically, the bilocular cyst, near the junction of larynx and trachea, had an epithelial lining of bronchogenic and esophageal origin. Concomitant malformation of the laryngeal muscles and cartilage resulted in a combination of anomalies that have not been reported in the human or veterinary literature.

Paratracheal air cyst in a foal

“…Ultimobranchial thyroid cyst (Ostergaard et al 2014), thyroglossal duct cyst (Kelmer et al 2007), branchial cyst (David et al 2008), bronchogenic cyst, and oesophageal and tracheal duplication cysts (Peek et al 1995;Matsuda et al 2010) can all be differentials for ventral cervical cysts in horses. Ultimobranchial thyroid cysts are of C cell origin, are located in the thyroid region and have a thick fibrous capsule lined by keratinising stratified squamous epithelium (Ostergaard et al 2014).…”

“…1995; Matsuda et al . 2010) can all be differentials for ventral cervical cysts in horses. Ultimobranchial thyroid cysts are of C cell origin, are located in the thyroid region and have a thick fibrous capsule lined by keratinising stratified squamous epithelium (Ostergaard et al .…”

“…Congenital masses of the cranial neck in horses are rare (Uberreiter 1968;Nolen-Walston et al 2009). In foals, differential diagnoses for cranial neck swelling should include congenital abnormalities such as guttural pouch tympany (Blazyczek et al 2004); branchial remnant cyst (Nolen-Walston et al 2009); oesophageal, tracheal and bronchial duplication cysts (Peek et al 1995;David et al 2008;Matsuda et al 2010); or thyroglossal cysts (Uberreiter 1968). Although clinical history and examination may suggest a diagnosis, imaging and/or histology is required to confirm the clinical diagnosis and assess the anatomical extent of the lesion (Nolen-Walston et al 2009).…”

“…2008; Matsuda et al . 2010); or thyroglossal cysts (Uberreiter 1968). Although clinical history and examination may suggest a diagnosis, imaging and/or histology is required to confirm the clinical diagnosis and assess the anatomical extent of the lesion (Nolen‐Walston et al .…”

Esophageal cyst in the duodenum of a foal

“…12 Cystic CFMs have been described in cats, cattle, dogs, horses, and monkeys. [1][2][3][4]6,7,10,11,[13][14][15][16][17][18]20 These malformations have been identified in various locations, have a wide range of wall features and epithelial linings, and have been named by various denominations ( Table 1). The esophageal cyst, in the foal reported herein, differed from those previously described in the veterinary literature in that the cyst was located in the duodenum and the cyst was lined by mixed squamous and simple cuboidal to columnar epithelium.…”