Bronchoalveolar lavage fluid cytological findings in healthy Amiata donkeys

Vitale, Valentina; Bonelli, Francesca; Briganti, Angela; Sgorbini, Micaela

doi:10.4314/ovj.v11i1.23

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…With the development of modern diagnostic methods, the bronchoalveolar lavage method can improve the clinical diagnostic efficiency by collecting the alveolar surface fluid and diagnosing the relevant markers. The relevant markers in the bronchoalveolar lavage fluid appear earlier and have high concentrations, thus becoming an emerging clinical diagnostic method [ 4 , 5 ]. In this study, the levels of CEA and ProGRP in the BALF of the patients with lung cancer were significantly higher than those of the control group, indicating that the levels of CEA and ProGRP were significantly increased in patients with lung cancer.…”

Section: Discussionmentioning

confidence: 99%

Detection of CEA and ProGRP Levels in BALF of Patients with Peripheral Lung Cancer and Their Relationship with CT Signs

Tian

Qin

2022

BioMed Research International

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Background. Lung cancer is a common clinical thoracic malignant tumor, which had a serious impact on the safety of patients, currently ranking first in all malignant tumors in morbidity and mortality, with generally less than 5% survival rate in 5 years. Objective. To investigate the relationship and significance between carcinoembryonic antigen (CEA) and precursor gastrin-releasing peptide (ProGRP) changing levels in bronchoalveolar lavage fluid (BALF) and CT imaging features in patients with peripheral lung cancer. Methods. A total of 90 patients diagnosed with peripheral lung cancer as the lung cancer group and 60 patients with benign lung diseases as the control group in our hospital from May 2019 to October 2021 were selected to compare the differences of CEA and ProGRP in BALF by the classification of CT features. Results. The levels of CEA and ProGRP in the BALF of the lung cancer group were significantly higher than those of the control group; the proportion of patients with lobulation sign, burr sign, ground glass sign, pleural effusion, and lesion diameter ≥ 3.0 cm in the lung cancer group was higher than that in the control group; the CEA level in BALF of lung cancer patients with spicule sign, pleural effusion, and lesion diameter ≥ 3.0 cm was significantly higher than that without these symptoms, while ProGRP level in the BALF of lung cancer patients with lobulation sign, burr sign, ground glass sign, pleural effusion, and lesion diameter ≥ 3 . 0 cm was significantly higher than that of lung cancer patients without these symptoms. Conclusion. The check of CEA and ProGRP in BALF in combination with CT features has a certain clinical value for the diagnosis of lung cancer. At the same time, the increased levels of CEA and ProGRP in BALF have a certain correlation with the changes of malignant signs of lung cancer in CT examination.

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Section: Discussionmentioning

confidence: 99%

Detection of CEA and ProGRP Levels in BALF of Patients with Peripheral Lung Cancer and Their Relationship with CT Signs

Tian

Qin

2022

BioMed Research International

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“…Em experimento, Vitale et al (2021) realizaram a lavagem bronco alveolar por tubo naso traqueal sem o auxílio do broncoscópio. Inicialmente, um tubo, com três metros de comprimento, dez milímetros de diâmetro e, com um cuff na sua extremidade distal, foi guiado através da cavidade nasal até a bifurcação da traqueia.…”

Section: Lavagem Bronco Alveolar (Lba)unclassified

Coleta e avaliação das secreções de vias aéreas posteriores em equinos: Revisão

Pereira¹,

Oliveira²,

Martins³

et al. 2022

Pubvet

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As enfermidades respiratórias causam grandes impactos na equinocultura. A determinação do diagnóstico das afecções de caráter inflamatório do sistema respiratório inferior (ou posterior) de equinos depende da associação de histórico e exame clínico em conjunto com os exames complementares, portanto, as intervenções realizadas por profissionais veterinários devem estar sempre amparadas por bons métodos diagnósticos para que seja instituído o tratamento adequado. Como exames complementares, as secreções de vias aéreas inferiores podem ser submetidas a citologia, cultura bacteriana, análise bioquímica, isolamento viral e testes moleculares. Dentre os métodos de coleta destaca-se a utilização das técnicas transtraqueais, entre elas, a lavagem e aspiração transtraqueal percutânea (LPP), a aspiração transtraqueal percutânea (ATP) e a lavagem e aspiração transtraqueal endoscópica (LTE). Além das técnicas transtraqueais, é possível a realização da lavagem broncoalveolar, sendo esta última capaz de colher amostras das vias respiratórias menores e mais distais. O presente estudo visou reunir as principais informações sobre as técnicas de coleta e avaliação das secreções das vias aéreas inferiores em equinos, podendo servir como material auxiliar ao diagnóstico por parte de profissionais veterinários.

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