Bronchiolitis obliterans organizing pneumonia–Experience of a pulmonology ward

Fonseca, Ana Mafalda; Meruje, Manuela; Barata, Fernando; Martins, Yvette; Pires, Jorge; Castro, Lígia

doi:10.1016/s2173-5115(07)70337-8

Cited by 3 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…COP patients typically present with cough, dyspnea, and fever, and crackles are commonly heard on auscultation while wheezing lung sounds are rarely noted. On pulmonary function tests, restrictive ventilatory defects and a decrement in the carbon monoxide diffusing capacity (DL CO ) are typically observed 10,[12][13][14][15] . However, manifestations of organizing pneumonia can be seen in several conditions, such as infectious lung disease, inflammatory bowel disease, connective tissue disease, myeloproliferative disorder, graft-versus-host disease, drug reactions, or after undergoing radiation therapy.…”

Section: Clinical Manifestationmentioning

confidence: 99%

“…On chest HRCT, consolidation along the subpleural area and the bronchovascular bundle was the most common finding and was noted in nearly half of the cases, mostly bilateral, and usually invades the lower portion of the lungs 9,12,14,[16][17][18] .…”

Section: Radiologic Findingsmentioning

confidence: 99%

“…However, several studies have reported rapid clinical improvement after glucocorticoid steroid treatment. The starting dosage for methylprednisolone or prednisone ranges from 0.5-1 mg/kg, gradually tapering off after a few weeks 10,14,17 .…”

Section: Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia

2021

View full text Add to dashboard Cite

show abstract

Section: Clinical Manifestationmentioning

confidence: 99%

Section: Radiologic Findingsmentioning

confidence: 99%

See 1 more Smart Citation

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia

2021

View full text Add to dashboard Cite

show abstract

“…A bronquiolite obliterante com pneumonia em organização (BOPO) é uma doença com manifestações clínicas, radiológicas e prognóstico peculiares, mas que podem se assemelhar a outras alterações patológicas intersticiais pulmonares (de Almeida et al, 2002;Addor et al, 2004;Cordier, 2006;Fonseca et al, 2007;Moraes et al, 2021). A BOPO é uma doença reportada mundialmente, com aproximadamente 1,6 casos para 100.000 habitantes e entre 6-7 casos para 100.000 internações, responsável por aproximadamente 20%-30% dos casos de doenças pulmonares infiltrantes (Cazzato et al, 2000;Alsaghir et al, 2007).…”

Section: Introductionunclassified

Bronquiolite obliterante com pneumonia em organização: relato de caso envolvendo um diagnóstico diferencial

Macedo

Lobo

Barbosa

et al. 2021

RSD

View full text Add to dashboard Cite

A bronquiolite obliterante com pneumonia em organização (BOPO) é uma entidade com sugestivo diagnóstico clínico e por imagem associado à evidência de tecido conjuntivo no lúmen dos espaços aéreos distais dos pulmões. Aqui abordamos um caso de BOPO e destacamos a importância do diagnóstico diferencial. Paciente do sexo masculino, 76 anos, ex-fumante (interrompeu o hábito há cerca de 30 anos), desenvolveu queixas de tosse copiosa e não produtiva, febre termometrada de 38 ºC e emagrecimento sem alívio ao uso de fenoterol + brometo de ipatrópio. Paciente sem histórico recente de infecção, nega uso de drogas sistêmicas/inaladas, e não realizou viagens recentes. Relatou relevante histórico familiar para o câncer. Exame físico: “Bom estado geral” (B.E.G. ativo e reativo), hipocorado, acianótico, anictérico, afebril, eupneico e sem sinais de desconforto respiratório com Sat O2 = 98%. Percussão com som claro pulmonar. Ausculta sibilante em bases pulmonares e roncos esparsos, em hemitórax esquerdo (HTE). Exame espirométrico com normalidade dos parâmetros, com parcial variação de volume após o uso de broncodilatador. A tomografia computadorizada de alta resolução (TCAR) de tórax apresentou áreas de consolidação no espaço aéreo, bilaterais e assimétricas com predominância nas regiões peribronquicas, algumas assumindo aspecto de nódulos pulmonares circundadas por vidro fosco. Posteriormente, no diagnostico diferencial, a tomografia computadorizada por emissão de pósitrons (PET-CT) revelou um processo inflamatório em fase resolutiva, descartando outras doenças, por exemplo, o adenocarcinoma pulmonar. Optou-se pela prescrição de Prednisona e o acompanhamento do quadro com Radiografias de tórax que, após 4 meses, mostrava padrões dentro da normalidade. Atualmente o paciente se encontra bem e com remissão total dos sintomas e sob terapêutica contínua.

show abstract

“…Systemic steroid therapy is recommended to treat idiopathic nonspeci c interstitial pneumonia, and 5-year survival has been reported to be greater than 70% [3][4][5]. Cryptogenic organizing pneumonia also has good response to systemic steroid therapy [6,7]. Less than 5% of patients with cryptogenic organizing pneumonia progress to acute respiratory failure or death [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Longitudinal comparison of anxiety and depression between idiopathic pulmonary fibrosis and other interstitial lung diseases: a prospective cohort study

Bae

Cho

Lee

et al. 2020

Preprint

View full text Add to dashboard Cite

Background and objective: Few studies have investigated the differences in the incidence of anxiety and depression among the interstitial lung diseases (ILDs). We evaluated the differences in the incidence of anxiety and depression between idiopathic pulmonary fibrosis (IPF) and non-IPF ILD, and the changes after a 1-year follow-up period. Methods The study participants were patients included in a prospective ILD cohort of Seoul National University Hospital between March 2013 and August 2018. Clinical variables were recorded at baseline and at 1 year. The Hospital Anxiety and Depression Scale was used to assess patient anxiety and depression at baseline and at 1-year follow-up. Results A total of 224 patients in the cohort participated in the study (154 [68.8%] with IPF and 70 [31.2%] with non-IPF ILD). Among them, 111 patients completed a follow-up Hospital Anxiety and Depression Scale questionnaire 1 year later (77 in the IPF group, 34 in the non-IPF group). In the IPF group, 20.8% and 27.3% of patients suffered from anxiety and 29.9% and 31.2% suffered from depression at baseline and 1-year follow-up, respectively. In the non-IPF group, 14.3% and 23.5% of patients suffered from anxiety and 24.3% and 17.6% suffered from depression at baseline and 1-year follow-up, respectively. Total score on the St. George’s Respiratory Questionnaire at baseline was associated with depression both at baseline (odds ratio 1.05; 95% confidence interval 1.02–1.08) and at 1-year follow-up (odds ratio 1.03; 95% confidence interval 1.00-1.05), even after adjusting other factors. The interaction of prevalence change of anxiety and depression at baseline and 1-year follow-up between the IPF group and the non-IPF ILD group were not statistically significant (p-value 0.878 for anxiety and 0.376 for depression, respectively). Conclusion The prevalence of anxiety and depression at baseline and at 1-year follow-up were not significantly different between patients with IPF and non-IPF ILD. St. George’s Respiratory Questionnaire total score at baseline was associated with depression at baseline and at 1-year follow-up.

show abstract

Bronchiolitis obliterans organizing pneumonia–Experience of a pulmonology ward

Cited by 3 publications

References 8 publications

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia

Bronquiolite obliterante com pneumonia em organização: relato de caso envolvendo um diagnóstico diferencial

Longitudinal comparison of anxiety and depression between idiopathic pulmonary fibrosis and other interstitial lung diseases: a prospective cohort study

Contact Info

Product

Resources

About