Bronchiolar Carcinoma (Alveolar Cell), Another Great Imitator; A Review of 41 Cases

Ludington, Louis G.; Verska, Joseph J.; Howard, Thora; Kypridakis, George; Brewer, Lyman A.

doi:10.1378/chest.61.7.622

Cited by 60 publications

(14 citation statements)

References 11 publications

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“…The incidence of bronchio-alveolar carcinoma as a percentage of all lung cancer varied from 1.1 [Knudson et al, 1965] to 9.0% [Ludington et al, 1972] in the reports reviewed. Percentages as low as 0.4 were cited in the early literature [Storey et al, 1953], but are likely biased by a poor awareness of bronchioalveolar carcinoma as distinct from adenocarcinoma.…”

Section: Resultsmentioning

confidence: 99%

“…Early reports propounding a multicentric origin [Storey et al, 1953, Delarue andGraham, 1949] appear to have been biased by observation of predominately faradvanced cases. Studies published during the 1960s began to question the concept of multicentric origin [Hawkins et al, 1963, Knudson et al, 1965, The re cent literature, including the large number of cases reported having solitary resectable lesions, decisively refutes this concept [Ludington et al, 1972, McNamara et al, 1969, Munnell et al, 1978.…”

Section: Discussionmentioning

confidence: 99%

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Bronchio-Alveolar Carcinoma

Edgerton¹,

Rao²,

Takita³

et al. 1981

Oncology

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Bronchio-Alveolar Carcinoma

Edgerton¹,

Rao²,

Takita³

et al. 1981

Oncology

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“…The erythrocyte sedimentation rate was 29 mm/hour. Breathing room air, blood gas tensions were Pao, 6 2 kPa, Paco2 4-5 kPa, and pH 7'45.…”

Section: Case Historymentioning

confidence: 95%

Respiratory failure with diffuse patchy lung infiltrates: an unusual presentation of squamous cell carcinoma

Meysman

Schoors

Reynaert

et al. 1994

Thorax

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The case history is presented of a patient with squamous cell carcinoma of the lung with diffuse bilateral pulmonary shadowing mimicking bronchioloalveolar ceil carcinoma which led to type I respiratory failure. (Thorax 1994;49:1271-1272 A chest radiograph showed diffuse patchy opacities involving both lung fields, paratracheal lymphadenopathy, a moderate increase in heart diameter, and no evidence of pleural disease (fig 1).Microbiological examination of sputum and blood were negative. Fibreoptic bronchoscopy revealed diffuse non-specific inflammatory changes of the mucosa which was most pronounced in the lower lobes. No

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“…Many patients have the symptoms of cough, chest pain, and sputum production, which make it more difficult to distinguish BAC from infectious pneumonia and other pulmonary inflammatory processes (5). Most pneumonictype adenocarcinomas (P-ADCs) contained a mixture of BAC and other histologic subtypes, including an invasive component (6). This case report describes a patient with recurrent lesions in left lower lung, and repeated symptoms of cough, sputum production for about 8 years, who was finally diagnosed as high differentiated adenocarcinoma.…”

Section: Introductionmentioning

confidence: 98%

Recurrent “pneumonia” in left lower lobe lasting for 8 years: a case report

Yuan¹,

Yao²,

Li³

et al. 2016

Transl. Lung Cancer Res.

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Bronchioloalveolar carcinoma (BAC) is a unique lung neoplasm with variable forms, such as single nodular, multifocal and lobar pneumonic types. The pneumonic type BAC is often difficult to differentiate from pneumonia. Here we present a case of 63-year-old Chinese male, who had recurrent cough, white sputum with pneumonic lesions in left lower lobe. He suffered from lung biopsies for three times, and finally diagnosed as high differentiated adenocarcinoma 8 years later. He was treated with four cycles of pemetrexed and cisplatin, and four cycles of docetaxel and nedaplatin. However, he did not achieve disease stabilization and is still under follow up. This case suggests that, pneumonic type adenocarcinoma may radiographically and clinically resemble infectious pneumonia. Lack of fever and leukocytosis, no response to antibiotics, air bronchogram, and accompanied nodules or patches in computed tomography (CT) scans should raise suspicion about the diagnosis of pneumonia. Lung biopsy might be the only means of ruling in a diagnosis of BAC.

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Bronchiolar Carcinoma (Alveolar Cell), Another Great Imitator; A Review of 41 Cases

Cited by 60 publications

References 11 publications

Bronchio-Alveolar Carcinoma

Bronchio-Alveolar Carcinoma

Respiratory failure with diffuse patchy lung infiltrates: an unusual presentation of squamous cell carcinoma

Recurrent “pneumonia” in left lower lobe lasting for 8 years: a case report

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