Bronchiectasis in yellow nail syndrome

Woodfield, Georgia; Nisbet, Mitzi; Jacob, Joe; Mok, Wing Yan; Loebinger, Michael R.; Hansell, David M.; Wells, Adrian; Wilson, Robert

doi:10.1111/resp.12866

Cited by 35 publications

(30 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For example, Down syndrome may be associated with immunodeficiency, incoordinate swallow, GOR and tracheomalacia . Other syndromes which may be complicated by bronchiectasis include Marfan's, Yellow Nail (typical dystrophy, may be a positive family history and lymphoedema), velocardiofacial, ataxia telangiectasia (also multifactorial, immunodeficiency and incoordinate swallow both contributing), Mounier‐Kuhn (tracheobronchomegaly) and Williams Campbell syndrome (congenital bronchomalacia) . Ataxia telangiectasia presents particular diagnostic problems because of the radiosensitivity of these patients, limiting the amount of diagnostic X‐rays which can be performed.…”

Section: Causes Of Bronchiectasismentioning

confidence: 99%

Pathophysiology, causes and genetics of paediatric and adult bronchiectasis

Bush

Floto

2019

Respirology

View full text Add to dashboard Cite

Bronchiectasis has historically been considered to be irreversible dilatation of the airways, but with modern imaging techniques it has been proposed that 'irreversible' be dropped from the definition. The upper limit of normal for the ratio of airway to arterial development increases with age, and a developmental perspective is essential. Bronchiectasis (and persistent bacterial bronchitis, PBB) is a descriptive term and not a diagnosis, and should be the start not the end of the patient's diagnostic journey. PBB, characterized by airway infection and neutrophilic inflammation but without significant airway dilatation may be a precursor of bronchiectasis, and there are many commonalities in the microbiology and the pathology, which are reviewed in this article. A high index of suspicion is essential, and a history of chronic wet or productive cough for more than 4-8 weeks should prompt investigation. There are numerous underlying causes of bronchiectasis, although in many cases no cause is found. Causes include post-infectious, especially after tuberculosis, adenoviral or pertussis infection; aspiration syndromes; defects in host defence, which may solely affect the airways (cystic fibrosis, not considered in this review, and primary ciliary dyskinesia); and primary ciliary dyskinesia or be systemic, such as common variable immunodeficiency; genetic syndromes; and anatomical defects such as intraluminal airway obstruction (e.g. foreign body), intramural obstruction (e.g. complete cartilage rings) and external airway compression (e.g. by tuberculous lymph nodes). Identification of the underlying cause is important, because some of these conditions have specific treatments and others genetic implications for the family.

show abstract

Section: Causes Of Bronchiectasismentioning

confidence: 99%

Pathophysiology, causes and genetics of paediatric and adult bronchiectasis

Bush

Floto

2019

Respirology

View full text Add to dashboard Cite

show abstract

“…11 Plevral efüzyon hastaların %14-46'sında, bronşektazi ise %44'ünde görülmektedir. 12,13 STS hastalarındaki plevral efüzyonları değerlendiren bir derlemede; plevral sıvının hastaların %68,3'ünde bilateral, %95'inde eksüda vasıflı ve lenfosit hâkimiyetinde olduğu bildirilmiştir. 14 13 Olgumuzda öksürük semptomu ve BT'de kronik bronşitik değişiklikleri mevcuttu.…”

Section: Sarı Tırnak Sendromuunclassified

“…Grip ve pnömokok aşıları kuvvetle önerilmektedir. 13 Olgumuzda kronik bronşit semptomları mevcut olup; uygun hidrasyon, postüral drenaj eğitimi ve aşılar konusunda bilgi verilmiştir.…”

Section: Olgu Sunumuunclassified

Yellow Nail Syndrome

Aktürk¹,

Karabatak²,

Barış³

et al. 2019

Turkiye Klinikleri J Health Sci

View full text Add to dashboard Cite

arı tırnak sendromu (STS); nadir görülen, çoğunlukla otozomal dominant geçiş gösteren bir hastalıktır. Hastalığın klasik üç bulgusu; sarı renkli tırnaklar, lenfödem ve plevral efüzyondur. 1 Bu sendrom ilk kez 1964 yılında Samman ve White tarafından; tırnaklarda yavaş büyüme-sarı renk değişikliği ve periferik ödem kliniğiyle tanımlanmıştır. 2 Daha sonra Emerson tarafından da plevral efüzyon eklenerek hastalığın klasik triadı oluşturulmuştur. 3 STS tanısı genellikle puberte sonrası konulmakla birlikte, nadiren çocukluk çağında da tanınabilmektedir. 4 Etiyolojisi bilinmeyen bu sendromun patofizyolojisinde en çok bozulmuş lenfatik drenaj sorumlu tu

show abstract

“…It is primarily diagnosed clinically, and when 2 of the 3 cardinal signs are present, it is treated as incomplete YNS in general. 1 Associated respiratory manifestations include pleural effusion and chronic respiratory tract infections such as chronic rhinosinusitis (CRS) and bronchiectasis 2 ; however, the mechanism of interplay between respiratory tract infections and nail lesions remains to be clarified. In addition, few reports have been published regarding YNS with CRS compared with reports on other respiratory diseases, indicating a low level of recognition of YNS among otorhinolaryngologists.…”

Section: Introductionmentioning

confidence: 99%

“…Conversely, treatment of concomitant respiratory manifestations such as bronchiectasis reportedly results in improvement of yellow nails. 2 Although the relationships between these manifestations and yellow nails, as well as the detailed mechanism of the pathological condition, are unclear, these findings suggest that the respiratory manifestations may act as focal infections exerting some kind of adverse effect on the nails.…”

Section: Introductionmentioning

confidence: 99%

Yellow Nail Syndrome With Dramatic Improvement of Nail Manifestations After Endoscopic Sinus Surgery

Hosokawa

Kuboki

Mori

et al. 2017

Clin Med Insights Ear Nose Throat

View full text Add to dashboard Cite

Objectives:Yellow nail syndrome (YNS) is a rare disease of unknown cause characterized by the triad of yellow nails, respiratory manifestations, and lymphedema. Although several therapies for YNS have been reported, there is no common consensus in the treatment. In this case report, we present a case of 56-year-old woman with YNS, whose nail manifestation was dramatically improved after endoscopic sinus surgery for the treatment of chronic rhinosinusitis.Methods:Endoscopic sinus surgery involving middle meatal antrostomy was performed for the case of YNS with chronic rhinosinusitis and bronchiectasis resistant to antibacterial drugs.Results:A month after the surgery, the patient’s nails eventually showed dramatic improvement.Conclusions:Otorhinolaryngologists should recognize that chronic rhinosinusitis can be a symptom of YNS, and that the aggressive treatment including surgical approach for chronic rhinosinusitis may be a useful in the control of nail manifestation in YNS.

show abstract

Bronchiectasis in yellow nail syndrome

Abstract: Background and objective: Yellow nail syndrome (YNS) is a rare and poorly described disease process. In this case-control study, clinical features and findings on HRCT were compared with idiopathic bronchiectasis (IBx).

Cited by 35 publications

References 33 publications

Pathophysiology, causes and genetics of paediatric and adult bronchiectasis

Pathophysiology, causes and genetics of paediatric and adult bronchiectasis

Yellow Nail Syndrome

Yellow Nail Syndrome With Dramatic Improvement of Nail Manifestations After Endoscopic Sinus Surgery

Contact Info

Product

Resources

About