Bronchiectasis in alpha1-antitrypsin deficiency

Augmentation therapy with human alpha-1-proteinase inhibitor reduces exacerbations in patient with bronchiectasis and alpha-1-antitrypsin deficiency

“…The data concerning the association between bronchiectasis and AATD is contradictory. Some authors describe a higher frequency of bronchiectasis in patients suffering from AATD [ [8] , [9] , [10] , [11] ], and Araujo et al reported that the severity of AATD correlated with the severity of bronchiectasis [ 12 ]. However, there are also reports that AATD and bronchiectasis do not correlate [ [13] , [14] , [15] ].…”