Bronchial Geotrichosis with Fungemia Complicating Bronchogenic Carcinoma

Ghamande, Anant R.; Landis, Francis B.; Snider, Gordon L.

doi:10.1378/chest.59.1.98

Cited by 14 publications

(13 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Catheter‐associated infection caused by G. candidum has been reported rarely (Table 1) (3–8, 10–14). In addition to a positive blood culture and skin biopsy of the eschar that was adjacent to the tunneled catheter, Geotrichum species also grew from the sputum, which most likely represented lower respiratory tract infection given the finding of nodular pneumonia on chest CT.…”

Section: Discussionmentioning

confidence: 99%

“…Reports were excluded if no species was identified, or if G. candidum was obtained only from sputum samples or non‐sterile sites, which could have represented colonization or contamination. Eight of the 12 cases reported since 1971 involved patients with underlying malignancy, many of whom had recent chemotherapy (5–8, 10–12, 14). Five patients had an underlying hematologic malignancy, at least 3 of whom were neutropenic.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Disseminated Geotrichum candidum infection in a patient with relapsed acute myelogenous leukemia following allogeneic stem cell transplantation and review of the literature

Henrich

Marty

Milner

et al. 2009

Transplant Infectious Dis

View full text Add to dashboard Cite

We describe a woman with relapsed acute myelogenous leukemia after allogeneic stem cell transplantation who developed disseminated Geotrichum candidum infection during chemotherapy-induced neutropenia. The isolate was susceptible to voriconazole, amphotericin B, and micafungin in vitro. We review the literature regarding invasive infections with G. candidum, which predominantly affect immunocompromised hosts, and discuss potential therapies for this rare pathogen.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Disseminated Geotrichum candidum infection in a patient with relapsed acute myelogenous leukemia following allogeneic stem cell transplantation and review of the literature

Henrich

Marty

Milner

et al. 2009

Transplant Infectious Dis

View full text Add to dashboard Cite

show abstract

“…The significance of this particular case was questioned, however, and culture documentation of widespread G. candidum infection was not presented (4,8). Evidence for dissemination in six other reported cases is lacking (1,5,7,10,11). All six patients had self-limited fungemia.…”

mentioning

confidence: 87%

“…The therapy and outcome of Geotrichum infections are dependent on the degree of invasion of the organism and the status of the host. Ghamande et al recommended no therapy with amphotericin B in view of the usual benign course of geotrichosis (5). Sheehy et al suggested that Geotrichum spp.…”

mentioning

confidence: 99%

Disseminated Geotrichum candidum infection

Kassamali

Anaissie

et al. 1987

J Clin Microbiol

View full text Add to dashboard Cite

The pathogenicity of the fungus Geotrichum candidum in humans has not been clearly defined. A patient with acute leukemia who developed a fatal disseminated G. candidum infection while neutropenic is described. At autopsy examination, this patient was misdiagnosed on the basis of histopathology as having disseminated candidiasis until G. candidum was isolated from postmortem culture specimens. The emergence of this organism as an occasional pathogen in leukemic patients is of interest and illustrates the importance of obtaining fungal cultures. There is a need for more effective drugs for antifungal prophylaxis and therapy.

show abstract

“…Infective fungal endocarditis is a severe opportunistic infection with a high mortality rate of about 50%. [ 2 ] Among yeasts, various candida species, Trichosporon species, Saccharomyces cervisiae has been reported. Table 1 summarizes reported cases of infective endocarditis in which Geotrichum and its synonyms have been isolated.…”

mentioning

confidence: 99%