Bronchial carcinoma and long-term survival. Retrospective study of 433 patients who underwent resection.

Abstract

Freise, G., Gabler, A., and Liebig, S. (1978). Thorax, 33,[228][229][230][231][232][233][234] (Table 1). Thirty-eight patients (8%) had tumours which were not resectable. Sixty-three (13-4%) died within the first four weeks after operation. Follow-up was not possible after discharge from hospital in 10 cases. The remaining 398 patients were followed up at outpatient consultations or from information sent by practitioners or other hospitals. One hundred and twenty-five patients (28-9%) survived five years; this survival rate is similar to those in other published studies. ResultsThe incidence of bronchial carcinoma in women is less than in men. In our series, females represented 10% of all thoracotomies, which is an average rate (Buchberger and Jenny, 1967;Sriboonma, 1967;Kutschera, 1968). The reason why women have a better prognosis (Berndt, 1965;Watson, 1965) is uncertain. Our five-year survival rate in women is 34% and in men 27%. The women

Predictors of Survival in Patients With Bone Metastasis of Lung Cancer

“…Many patients with lung cancer are in advanced stages of the disease at the time of diagnosis. The 5-year survival rate for patients with lung cancer is 10% to 20%, as reported by Stanley [15] and Freise et al [4], indicating a poor prognosis. Although it is reported bone metastasis from lung cancer occurs in 14% to 40% of patients, its clinical features have not been clearly described [9].…”

“…The univariate log rank test was used to evaluate the prognostic importance of age, gender, PS, histologic type, condition of the primary site, number of bone metastases, site of bone metastasis, pathologic fractures, metastasis to the brain or liver, chemotherapy or radiotherapy for the primary site, and use of an EGFR inhibitor (gefitinib). Subsequent multivariate analysis was performed to detect factors independently associated with survival using a Cox proportional hazard survival model [4]. Multivariate regression analysis was performed by including all clinical characteristics that independently predicted 1-year survival.…”

Bronchioloalveolar carcinoma: The significance of two histopathologic types

“…A recognized risk to long-term survivors of resection for carcinomas of the lung is the development of second pulmonary carcinomas and carcinomas of another organ. [45][46][47][48] Some have considered that to accept a new lung carcinoma as a second primary, it should be of a different histologic type than the first lung ~arcinoma.~' We believe that this definition may be too strict, and we think that two of the patients in our series may have developed de nova BAC 55 and 63 months, respectively, following surgical removal of their initial primary lung adenocarcinomas. In one of these the histologic pattern was strikingly similar to the original tumor.…”

The Impact of Superior Mediastinal Lymph Node Metastases on Prognosis in Non-small Cell Lung Cancer Located in the Right Middle Lobe

“…T he right middle lobe is the smallest lobe in the lung, and lung cancer originating there is much less common than in the other lobes, occurring in 3.8 to 6.7% of all lung cancers. [1][2][3][4] The fact that it is less common may be a reason that there are a few reports on the prognostic factors of middle lobe lung cancer.…”

“…Lymph drainage from the middle lobe extends to both superior and inferior mediastinal lymph nodes, and previous reports have demonstrated a high incidence of metastases to both the superior and inferior mediastinal zones. [1][2][3][4][5][6] Nevertheless, there are few articles on the relationships between status of hilar and mediastinal lymph node metastases and patient prognoses.…”