Brockenbrough–Braunwald–Morrow sign and Valsalva manoeuvre: how to unmask dynamic left ventricular outflow tract obstruction

Mabalukwa, Junior; Nguyen, Damien; Briki, Rachid; Audiat, Charles; Unger, Philippe

doi:10.1093/ehjci/jeac008

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“…For example, they may unmask latent dynamic LVOT obstruction. 10 In such cases, the diastolic filling time, end-diastolic volume, and hence the stroke volume are increased during the compensatory pause following the PVC, by the Frank-Starling mechanism. The increased contractility promotes LVOT obstruction, decreased pulse pressure, and increased LV pressure, a phenomenon known as the Brockenbrough-Braunwald-Morrow sign.…”

Section: Discussionmentioning

confidence: 99%