Broadband ultrasonic attenuation: are current measurement techniques inherently inaccurate?

Petley, Graham W.; Robins, P A; Aindow, J. D.

doi:10.1259/0007-1285-68-815-1212

Cited by 42 publications

(29 citation statements)

References 2 publications

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“…Indeed, when compared to the young, trabecular number is decreased and trabecular spacing increased in the elderly osteoporotic [27]. Higher BMD in the young may thus lead to greater 'phase cancellation' and exaggerated ultrasound attenuation [53], accentuating the discordance observed in correlation coefficients of QUS and BMD with age.…”

Section: Discussionmentioning

confidence: 99%

Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men

et al. 2012

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Section: Discussionmentioning

confidence: 99%

Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men

et al. 2012

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“…[1][2][3][4][5][6][7][8][9][10] Quantitative ultrasound parameters, such as speed of sound and broadband ultrasonic attenuation ͑BUA͒, have been shown to correlate with bone mineral density ͑BMD͒.…”

Section: Introductionmentioning

confidence: 99%

Inverse problems in cancellous bone: Estimation of the ultrasonic properties of fast and slow waves using Bayesian probability theory

Anderson

Bauer

Holland

et al. 2010

The Journal of the Acoustical Society of America

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Quantitative ultrasonic characterization of cancellous bone can be complicated by artifacts introduced by analyzing acquired data consisting of two propagating waves ͑a fast wave and a slow wave͒ as if only one wave were present. Recovering the ultrasonic properties of overlapping fast and slow waves could therefore lead to enhancement of bone quality assessment. The current study uses Bayesian probability theory to estimate phase velocity and normalized broadband ultrasonic attenuation ͑nBUA͒ parameters in a model of fast and slow wave propagation. Calculations are carried out using Markov chain Monte Carlo with simulated annealing to approximate the marginal posterior probability densities for parameters in the model. The technique is applied to simulated data, to data acquired on two phantoms capable of generating two waves in acquired signals, and to data acquired on a human femur condyle specimen. The models are in good agreement with both the simulated and experimental data, and the values of the estimated ultrasonic parameters fall within expected ranges.

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“…Other authors have addressed these issues in bone, and have demonstrated the artifacts inherent in phase sensitive measurements. 20,24,25 …”

Section: Introductionmentioning

confidence: 99%

Negative dispersion in bone: The role of interference in measurements of the apparent phase velocity of two temporally overlapping signals

Bauer

Marutyan

Holland

et al. 2008

The Journal of the Acoustical Society of America

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In this study the attenuation coefficient and dispersion ͑frequency dependence of phase velocity͒ are measured using a phase sensitive ͑piezoelectric͒ receiver in a phantom in which two temporally overlapping signals are detected, analogous to the fast and slow waves typically found in measurements of cancellous bone. The phantom consisted of a flat and parallel Plexiglas™ plate into which a step discontinuity was milled. The phase velocity and attenuation coefficient of the plate were measured using both broadband and narrowband data and were calculated using standard magnitude and phase spectroscopy techniques. The observed frequency dependence of the phase velocity and attenuation coefficient exhibit significant changes in their frequency dependences as the interrogating ultrasonic field is translated across the step discontinuity of the plate. Negative dispersion is observed at specific spatial locations of the plate at which the attenuation coefficient rises linearly with frequency, a behavior analogous to that of bone measurements reported in the literature. For all sites investigated, broadband and narrowband data ͑3-7 MHz͒ demonstrate excellent consistency. Evidence suggests that the interference between the two signals simultaneously reaching the phase sensitive piezoelectric receiver is responsible for this negative dispersion.

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Broadband ultrasonic attenuation: are current measurement techniques inherently inaccurate?

Cited by 42 publications

References 2 publications

Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men

Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men

Inverse problems in cancellous bone: Estimation of the ultrasonic properties of fast and slow waves using Bayesian probability theory

Negative dispersion in bone: The role of interference in measurements of the apparent phase velocity of two temporally overlapping signals

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