Broadband targeted UVB phototherapy for localized vitiligo: a retrospective study

Akar, Ahmet; Tunca, Mustafa; Koç, Erol; Kurumlu, Zafer

doi:10.1111/j.1600-0781.2009.00426.x

Cited by 19 publications

(15 citation statements)

References 5 publications

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“…These devices include 'BClear' that delivers broadband UVB, 'Multiclear' or 'Dualight' providing UVA and UVB combination and lastly 'Bioskin' which gives a NBUVB waveband peaking at 311nm [14][15][16]. Clinical studies have demonstrated that the results obtained are similar with the BB-UVB and NBUVB Targeted phototherapy devices in vitiligo [17].…”

Section: Discussionmentioning

confidence: 99%

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Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

Majid¹

2014

Pigmentary Disorders

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Section: Discussionmentioning

confidence: 99%

“…Targeted UV light-based therapies employ conventional noncoherent ultraviolet light that is delivered through fibre-optic cable systems specifically to the treatment area. These machines deliver the light energy in seconds and have larger spot sizes [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

Majid¹

2014

Pigmentary Disorders

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“…Treatment with microphototherapy can cause various tolerable adverse effects including erythema, blistering, hyperpigmentation, erosion, burning, and itching (3,6,(16)(17)(18). Therefore, in the present study the patients were asked about the occurrence of any of these side effects.…”

Section: Discussionmentioning

confidence: 99%

The efficacy of microphototherapy with a MedLight CupCUBEGrimed device in psoriatic patients with localized lesions

Yıldırım¹,

Erkin

2017

Turk J Med Sci

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Background/aim: Psoriasis is a chronic skin disease. To reduce side effects associated with current treatment modalities, new treatment methods are required. Some clinicians have begun to use microphototherapy to treat psoriatic patients with a limited number of lesions (lesions affecting <10% of the body surface area). Materials and methods:Microphototherapy is indicated in patients whose lesions persist despite systemic and topical treatment or when such treatment is contraindicated. Our study aimed to evaluate the efficacy of microphototherapy in psoriasis patients with localized lesions. Patients in this unblinded and prospective study were treated three times a week for 50 sessions using a MedLight CupCUBE Grimed microphototherapy device that emits an ultraviolet B (UVB) spectrum.Results: Forty-five lesions in 23 psoriatic patients were treated. Treatment outcome was evaluated based on the Psoriasis Severity Index (PSI). PSI scores decreased significantly during the treatment. Conclusion:The MedLight CupCUBE Grimed microphototherapy device was effective for the treatment of psoriasis patients with localized lesions. The device can administer UVB radiation to involved regions while protecting uninvolved regions and minimizing radiation dose. However, having to be administered by experienced technicians and the long time required for each treatment session are disadvantages of the technique.

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“…They reported repigmentation from a comparison of baseline photographs with those after 30 sessions by two independent investigators and they concluded that UVB microphototherapy seemed to be effective for the repigmentation of vitiligo in lesions located on the face instead of acral lesions. Akar et al 8 declared that despite the fact that the safety of targeted broadband UVB phototherapy in the treatment of localized vitiligo was good, its therapeutic effectiveness was limited and depended on the location of vitiligo lesions. To increase the efficacy, microphototherapy can be combined with other therapies.…”

Section: Discussionmentioning

confidence: 99%

“…Microphototherapy can cause various tolerable adverse effects including erythema, blistering, hyperpigmentation, erosion, burning and itching 8,[13][14][15][16] . Therefore, in this study, the patients were observed for the occurence of any of these side effects.…”

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confidence: 99%

The efficacy of microphototherapy in vitiligo patients with localized lesions

Yıldırım¹,

Erkin²

2017

TURKDERM

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©Copyright 2017 by Turkish Society of Dermatology and Venereology Turkderm-Turkish Archives of Dermatology and Venereology published by Galenos Yayınevi. ÖzBackground and Design: Vitiligo is a chronic skin disease. To reduce side effects associated with current treatment modalities, new treatment methods are required. Microphototherapy was introduced to treat vitiligo patients with a limited number of lesions (lesions affecting <10% of the body surface area). Materials and Methods: Our study has aimed to evaluate the efficacy of microphototherapy in vitiligo patients with localized lesions. In this unblinded and prospective study, patients were treated thrice weekly for at least 50 sessions using an MedLight CupCUBE Grimed ® microphototherapy device which emits ultraviolet B spectrum with a starting dose of 150 mJ/cm 2 for 5 seconds and with increments of 30 mj/cm 2 , 1 second at each session. At the end of the 50 th session, 50% reduction in Vitiligo Area Scoring Index (VASI) score was accepted as the required minimum response. Results: Thirty-three lesions from 14 patients were treated. Treatment outcome was evaluated based on the VASI. Between 0 th and 50 th sessions, the mean VASI score in 33 lesions decreased from 2.25 to 1.79 showing 20.4% decline (p<0.05). Twenty-one of 33 lesions exhibited decrease in VASI scores at the end of the 50 th session although only 11 of these 21 lesions reached the target of VASI 50% while the remaining 10 lesions did not reach the target. As a result, 11 lesions (33.3%) reached VASI 50% while the remaining 22 lesions (66.7%) did not reach the target. Conclusion: The efficacy of the MedLight CupCUBE Grimed ® microphototherapy device was poor with these starting doses, durations and increments for the treatment of patients with vitiligo who had localized lesions. Trying topical therapies initially, calculating minimal erythema dose and, thus, measuring the beginning ultraviolet doses and durations as a way to decrease the number of in-hospital sessions are feasible rather than applying this technique as the first option or alone in vitiligo patients with non-segmental and localized lesions. Keywords: Vitiligo, phototherapy, treatment Amaç: Vitiligo kronik bir deri hastalığıdır. Mevcut tedavi yöntemlerine bağlı oluşabilen yan etkileri azaltmak için yeni tedavi yöntemlerine ihtiyaç bulunmaktadır. Mikrofototerapi yöntemi sınırlı sayıda lezyona sahip (lezyonların vücut yüzey alanının %10'undan azını etkilemesi) vitiligo hastalarını tedavi etmek için kullanılmaya başlamıştır. Gereç ve Yöntem: Çalışmamız lokalize lezyonlara sahip vitiligo hastalarında mikrofototerapinin etkinliğini değerlendirmeyi hedeflemektedir. Prospektif olan ve kör olmayan bu çalışmada hastalara ultraviyole (UV) B ışını yayan MedLight CupCUBE Grimed ® mikrofototerapi cihazı ile başlangıç UV dozu 150 mJ/cm 2 ve 5 saniye, her seansta doz artımı 30 mj/cm 2 ve 1 saniye olacak şekilde haftada 3 kez en az 50 seans boyunca tedavi uygulanmıştır. Vitiligo Alan Skorlama İndeksi (VASİ) %50 (VASİ'de %50 azalma) 50 ...

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Broadband targeted UVB phototherapy for localized vitiligo: a retrospective study

Cited by 19 publications

References 5 publications

Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

Targeted NBUVB Phototherapy in Childhood Vitiligo: A Study in 35 Children

The efficacy of microphototherapy with a MedLight CupCUBEGrimed device in psoriatic patients with localized lesions

The efficacy of microphototherapy in vitiligo patients with localized lesions

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