Broadband Dielectric Spectroscopy as a Potential Label-Free Method to Rapidly Verify Ultraviolet-C Radiation Disinfection

Obeng, Yaw S.; Nablo, Brian J.; Reyes, Darwin R.; Poster, Dianne L.; Postek, Michael T.

doi:10.6028/jres.126.022

Cited by 2 publications

(2 citation statements)

References 29 publications

(45 reference statements)

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“…The portion of the transmitted signal exits the MUT with different magnitude and phase from the incident signal; thus, S21 and S12 also encode the phase difference between a transmitted signal and an incident signal. The Sparameters can be analytically transformed to produce the characteristic circuit element of the analyte, as described elsewhere [32]. Broadband microwave dielectric spectroscopy (BDS) measures the dispersive and dissipative dielectric behavior of the analyte as a function of frequency, i.e., changes in the polarizability of the analyte.…”

Section: Broadband Dielectric Spectroscopy (Bds) Backgroundmentioning

confidence: 99%

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

et al. 2022

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The most common gas sensors are based on chemically induced changes in electrical resistivity and necessarily involve making imperfect electrical contacts to the sensing materials, which introduce errors into the measurements. We leverage thermal- and chemical-induced changes in microwave propagation characteristics (i.e., S-parameters) to compare ZnO and surface-anchored metal–organic-framework (HKUST-1 MOF) thin films as sensing materials for detecting ethanol vapor, a typical volatile organic compound (VOC), at low temperatures. We show that the microwave propagation technique can detect ethanol at relatively low temperatures (<100 °C), and afford new mechanistic insights that are inaccessible with the traditional dc-resistance-based measurements. In addition, the metrological technique avoids the inimical measurand distortions due to parasitic electrical effects inherent in the conductometric volatile organic compound detection.

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Section: Broadband Dielectric Spectroscopy (Bds) Backgroundmentioning

confidence: 99%

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

et al. 2022

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“…As a result, DEP has been broadly applied on bioparticles such as DNA [ 16 ], RNA [ 17 ], proteins [ 18 ], bacteria [ 19 ], blood cells [ 20 ], and circulating tumor cells (CTCs) [ 21 ]. The electrical properties of cells can be measured using broadband dielectric spectroscopy (BDS) [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

New Generation Dielectrophoretic-Based Microfluidic Device for Multi-Type Cell Separation

2023

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This study introduces a new generation of dielectrophoretic-based microfluidic device for the precise separation of multiple particle/cell types. The device features two sets of 3D electrodes, namely cylindrical and sidewall electrodes. The main channel of the device terminates with three outlets: one in the middle for particles that sense negative dielectrophoresis force and two others at the right and left sides for particles that sense positive dielectrophoresis force. To evaluate the device performance, we used red blood cells (RBCs), T-cells, U937-MC cells, and Clostridium difficile bacteria as our test subjects. Our results demonstrate that the proposed microfluidic device could accurately separate bioparticles in two steps, with sidewall electrodes of 200 µm proving optimal for efficient separation. Applying different voltages for each separation step, we found that the device performed most effectively at 6 Vp-p applied to the 3D electrodes, and at 20 Vp-p and 11 Vp-p applied to the sidewall electrodes for separating RBCs from bacteria and T-cells from U937-MC cells, respectively. Notably, the device’s maximum electric fields remained below the cell electroporation threshold, and we achieved a separation efficiency of 95.5% for multi-type particle separation. Our findings proved the device’s capacity for separating multiple particle types with high accuracy, without limitation for particle variety.

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Broadband Dielectric Spectroscopy as a Potential Label-Free Method to Rapidly Verify Ultraviolet-C Radiation Disinfection

Cited by 2 publications

References 29 publications

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

New Generation Dielectrophoretic-Based Microfluidic Device for Multi-Type Cell Separation

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