British Society for Sexual Medicine Guidelines on Adult Testosterone Deficiency, with Statements for UK Practice

Abstract

Improving the diagnosis and management of TD in adult men should provide somatic, sexual, and psychological benefits and subsequent improvements in quality of life. Hackett G, Kirby M, Edwards D, et al. British Society for Sexual Medicine Guidelines on Adult Testosterone Deficiency, With Statements for UK Practice. J Sex Med 2017;14:1504-1523.

Erectile dysfunction and atrial fibrillation: A systematic review and meta‐analysis

“…Patient populations in two articles by Platek et al 10 and Szyma nski et al 17 were similar, and we included the study by Platek et al 10 as it provided more details and updated data for this meta-analysis. 18 Most of our studies defined ED by self-questionnaires, which included the IIEF and SHIM questionnaires. [8][9][10]12 The literature retrieval, review and selection process are shown in Figure 1.…”

Guideline of guidelines: testosterone therapy for testosterone deficiency

“…injections and s.c. pellets. The AUA, AACE, BSSM, and ISSM recommend against oral 17α alkylated testosterone because it can lead to hepatotoxicity . The AUA, EAU, BSSM, and AACE all recognise the risk of transference with topical TTh (Table ) .…”

“…However, there is concern in the literature that TTh can increase risk of major adverse cardiovascular events (MACE), such as MI or cerebrovascular accident. All guideline committees either comment that there is insufficient data in the literature that TTh increases the risk of MACE, or acknowledge the conflicting data (Table ) . Per the AUA guidelines, TTh should not be given to patients who have had a MI or stroke within the past 3–6 months .…”

“…The EAU uses a threshold of 350 ng/dL (12.1 nmol/L) for TT and 7 ng/dL (243 pmol/L) for free testosterone [2]. Similarly, the BSSM threshold is <345 ng/dL (12 nmol/L) for TT and <6.49 ng/dL (225 pmol/L) for free testosterone [7]. The ISSM and ISSAM also have a threshold of 350 ng/dL (12.1 nmol/L) [5,6].…”

BSSM guidelines on testosterone deficiency: a summary

“…1 Testosterone is the most important androgen in men, essential for developing and maintaining secondary male characteristics. 2 When testosterone levels fall, patients may experience adverse physical and psychological effects, which can compromise their general wellbeing, sexuality and fertility.…”