Irish Catholic primary education operates within a context increasingly marked by detraditionalisation and secularisation. As religious belief and identity recedes in Ireland, Catholic schools face challenges in enabling the children they serve to develop a personal relationship with God and nurturing their faith formation and development, an important element of the mission of the Catholic school. At the same time, mindfulness practice has grown exponentially in popularity across many sectors of society, including in Irish education. A growing body of research supports mindfulness practice in schools, citing benefits such as improved academic performance and enhanced wellbeing. This review examines the development of mindfulness practice in Irish Catholic primary schools. Curricular reform in primary education regarding the growing role of wellbeing is explored. The review also addresses opportunities and challenges to mindfulness practice in these schools.