British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

Sterling, Jane; Gibbs, Sam; Hussain, S. S. Haque; Mustapa, M.F. Mohd; Handfield‐Jones, S.

doi:10.1111/bjd.13310

Cited by 292 publications

(316 citation statements)

References 156 publications

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“…These findings confirm the role of environmental factors as reported by previous studies, with the presence of household animals contributing to poor standards of hygiene and thus favouring the spread of contagious skin diseases [19,23].…”

Section: Discussionsupporting

confidence: 92%

Prevalence and Risk Factors of Verruca Vulgaris among Primary School Children in Madinah and Jeddah, Saudi Arabia

Allayali¹,

Fallatah²,

Alorfi³

et al. 2017

J Clin Exp Dermatol Res

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Skin diseases are common contributors to disease morbidity worldwide, particularly among school children. Although skin diseases are rarely lethal, they can have a significant impact in terms of treatment cost, absence from school, and psychological distress. Verruca vulgaris (cutaneous warts) is a common skin problem in children that commonly affects the hands and feet.Objectives: This study aimed to determine the prevalence of warts among primary school children in Saudi Arabia to compare characteristics between children with and those without warts and to investigate the possible risk factors associated with the development of warts.Method: This school-based, cross-sectional study conducted among primary school children in the cities of Madinah and Jeddah, Saudi Arabia included 730 children, 298 males and 432 females, with mean age 11.2 ± 1.5 years from 15 randomly chosen public and private primary schools: eight public schools (four boys' and four girls') and two private schools (one boys' and one girls' school) from Madinah and five girls' schools from Jeddah (four public and one private). We collected data via interviews and a questionnaire and through the examination of each child's hands, feet, head, and neck for warts. Results:Our results showed that the prevalence of warts was 9.04%. Approximately 65% of the children with warts were boys. Nearly two-thirds (64%) of the children were found to have acute diseases. Boys and girls significantly differed regarding de novo and recurrent warts, with a higher proportion of de novo warts observed in boys. Boys tended to have a greater number of warts than girls, with the warts being smaller in size and persisting for longer durations, although these differences were not statistically significant. Risk factors were shown to be male sex, attending a public school, a large family size, smoking, working, sports activities, and handling domestic and farm animals at home. Having a highly-educated father appeared to reduce the risk. Conclusion:This study revealed a high prevalence of warts among primary school children in Madinah and Jeddah and elucidated the risk factors for the development of warts. This may help in the development of effective health messages about methods for preventing skin diseases. Keywords: Human papilloma virus; Plane warts; Verruca vulgaris Aim and ObjectivesAim: The aim of this study was to provide recent and valuable information about the epidemiology of verruca vulgaris among primary school children in Madinah and Jeddah. The information obtained will help to fill a gap in Saudi medical literature concerning this common skin disorder among school children and to tailor a health education program to combat it.Objectives: To determine the prevalence of warts among primary school children.To compare the characteristics of the participating children between those with and those without common warts.To investigate the possible risk factors associated with the development of warts among children.

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Section: Discussionsupporting

confidence: 92%

Prevalence and Risk Factors of Verruca Vulgaris among Primary School Children in Madinah and Jeddah, Saudi Arabia

Allayali¹,

Fallatah²,

Alorfi³

et al. 2017

J Clin Exp Dermatol Res

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“…Hence, multiple modalities like hypnosis/ suggestive therapy, cytodestructive treatments like electrocauterization, radiocauterization, chemical cauterization, cryotherapy, CO 2 laser ablation, virucidal therapies like topical gluteraldehyde, formaldehyde and cidofovir, antimitotic therapies like bleomycin, retinoids, podophyllin and podophyllotoxin, immunotherapies such as oral zinc sulfate, cimetidine, levamisole, topical dinitrochlorobenzene, diphencyprone, squaric acid dibutyl ester, intralesional interferon, imiquimod, BCG vaccine and HPV vaccines all have been tried. These treatment modalities have an average of 60-70% clearance of warts in 3 months 4 . Pain related to treatment, side effects and costs can be determining factors in choosing a therapy.…”

Section: Introductionmentioning

confidence: 99%

Study of Homologous Autoimplantation Therapy for Treatment of Multiple Warts in Patients Attending the Dermatology out Patient Department

Gugle¹,

Jadhav²,

Kote³

et al. 2015

mvpjms

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Introduction: Warts are benign tumours that commonly involve skin and other epithelial tissues. There is no single treatment modality that is 100% effective. In multiple warts, especially on face, palms, and soles destructive procedure are inappropriate and impractical. Homologous autoimplantation is a simple technique, which helps in inducing cell mediated response, causing clearance of warts. Aims and objectives: To evaluate the effect of homologous autoimplantation therapy in treatment of multiple warts. To study the untoward effects of this treatment. Material and methods: A total of 49 patients of viral warts were included in study. Homologous autoimplantation of wart was done and regular follow up was done to see the result. Results: Out of 49 patients, in 24 patients there was good response, 14 showed moderate response, 5 showed poor response and in 6 patients there was no response. Conclusion: Homologous autoimplantation is an easy, minimally invasive technique which clears multiple, recurrent and recalcitrant warts.

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“…2 Previous research has identified the ideal wart treatment as being able to resolve all warts with no recurrences, painlessly and without scarring. 3,4 Dermatologists will know that we are still some way from this version of utopia. Indeed, of several treatment options currently used, none is fully effective, and most involve pain, discomfort and also occasional scarring.…”

mentioning

confidence: 99%

“…3 According to recent consensus guidelines criteria, ECD is diagnosed by distinct pathological findings associated with radiological findings showing symmetric diaphyseal and metaphyseal osteosclerosis of the long bones found in more than 95% of cases, or other classic organ and sometimes iconic involvements such as dense infiltration of perinephric fat ('hairy kidney') or periaortic infiltration ('coated aorta'). 4 Moreover, extracutaneous or disseminated juvenile xanthogranuloma harbouring MAPK-activating mutation or ALK translocation are now considered to be ECD. 2 Histologically, ECD is characterized by polymorphic granulomas infiltrated by foamy histiocytes and by fibrosis or xanthogranulomatosis infiltrates of histiocytes.…”

mentioning

confidence: 99%

“…On immunohistochemical staining, ECD histiocytes are positive for CD68 and CD163 and negative for CD1a and CD207. 4 Therefore, ECD was first classified as non-Langerhans cell histiocytosis in the previous classification of histiocytosis. 5 The understanding of the pathophysiology of a closely related histiocytosis -Langerhans cell histiocytosis (LCH) -has been improved by the discovery of a recurrent BRAF V600E in about 55% of patients.…”

mentioning

confidence: 99%

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Treatment success in cutaneous warts: morphology and human papillomavirus type matter

Silling

Akgül

2018

Br J Dermatol

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The major advantage of the study is that the results reflect real-world impact of biologics by enrolling a diverse patient population, including groups often underrepresented in clinical trials (e.g. elderly patients or minorities). Furthermore, patients were allowed to switch between different biologics as well as to terminate biological therapy during the observation period. These real-life HRQoL results are not only valuable for clinical practice but also provide information for policy makers on the quality of care delivered to patients. 9 Moreover, cost-effectiveness analyses based on register data can better support reimbursement decision-making. Given the high costs associated with biologics, disease areas in which extensive patient registers are established may gain an advantage in competing for a fixed healthcare budget. With the growing number of biologics and biosimilars on the market, the real-world evidence systematically collected in psoriasis registers, such as the PsoReg and the British Association of Dermatologists' Biological Interventions Register, 10 is expected to become even more important in the coming years. AcknowledgmentsThe author is grateful to Prof. M arta P entek and Prof. L aszl o Gul acsi for their valuable comments on this manuscript. Conflicts of interestNone declared.

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British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

Cited by 292 publications

References 156 publications

Prevalence and Risk Factors of Verruca Vulgaris among Primary School Children in Madinah and Jeddah, Saudi Arabia

Prevalence and Risk Factors of Verruca Vulgaris among Primary School Children in Madinah and Jeddah, Saudi Arabia

Study of Homologous Autoimplantation Therapy for Treatment of Multiple Warts in Patients Attending the Dermatology out Patient Department

Treatment success in cutaneous warts: morphology and human papillomavirus type matter

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