Bright individuals: Applications of fluorescent protein‐based reporter systems in single‐cell cellular microbiology
Marc Schulte,
Luisa Grotheer,
Michael Hensel
Abstract:Activation and function of virulence functions of bacterial pathogens are highly dynamic in time and space, and can show considerable heterogeneity between individual cells in pathogen populations. To investigate the complex events in host–pathogen interactions, single cell analyses are required. Fluorescent proteins (FPs) are excellent tools to follow the fate of individual bacterial cells during infection, and can also be deployed to use the pathogen as a sensor for its specific environment in host cells or … Show more
“…article illuminate the challenges of imaging bacterial exit (Franzkoch et al, 2023;Schulte et al, 2024). We hope this collection of articles will stimulate the comparatively young field of pathogen exit or egress studies.…”
“…article illuminate the challenges of imaging bacterial exit (Franzkoch et al, 2023;Schulte et al, 2024). We hope this collection of articles will stimulate the comparatively young field of pathogen exit or egress studies.…”
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