Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons
Frank Raven,
Alexis Vega Medina,
Kailynn Schmidt
et al.
Abstract:Brief sleep loss can disrupt cognition, including information processing in neocortex and hippocampus. Recent studies have identified alterations in synaptic structures of principal neurons within these circuits. However, while in vivo recording and bioinformatic data suggest that inhibitory interneurons are more strongly affected by sleep loss, it is unclear how sleep and sleep deprivation affect interneuron synapses. Recent data suggest that activity among hippocampal somatostatin-expressing (SST+) interneur… Show more
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