Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower-Risk Infants: Executive Summary

Tieder, Joel S.; Bonkowsky, Joshua L.; Etzel, Ruth A.; Franklin, Wayne H.; Gremse, David A.; Herman, Bruce; Katz, Eliot S.; Krilov, Leonard R.; Merritt, J. Lawrence; Norlin, Chuck; Percelay, Jack M.; Sapién, Robert; Shiffman, Richard N.; Smith, Michael

doi:10.1542/peds.2016-0591

Cited by 48 publications

(44 citation statements)

References 5 publications

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“…ALTE was substituted with brief resolved unexplained event (BRUE). 6 BRUE concerns children under the age of 1 year that present with a short single resolved event. BRUE occurs in 1% of healthy children and 50% of these cases show severe episode without associated etiology.…”

Section: Discussionmentioning

confidence: 99%

Desaturation During Cry in the Neonatal Period

Salomon

Stelle

Korff

et al. 2018

Global Pediatric Health

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A 10-day-old boy was addressed to our unit by his pediatrician for intermittent stridor associated with frequent episodes of desaturation while crying. Prenatal and perinatal periods were uneventful and the baby was born at term (41 weeks of gestation) to a primipara mother. Neonatal adaptation was good (Apgar score 8/9/10). The baby was small for gestational age with a weight of 2985 g (third to 10th percentile). A hoarse cry was present from the second day of life. He was exclusively breastfed without fatigue or perspiration during feeding. The weight gain was adequate (20 g per day). At 10 days of life, the physical examination demonstrated stridor with costal retraction and 86% oxygen saturation while crying (maximum 90 seconds), reason for which the child was hospitalized for further investigations.

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Section: Discussionmentioning

confidence: 99%

Desaturation During Cry in the Neonatal Period

Salomon

Stelle

Korff

et al. 2018

Global Pediatric Health

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“…Infants dying of SIDS are known not to present any pre-mortem signs62 and there is an unclear association between a brief resolved unexplained event,63 formerly apparent life-threatening events64 and SIDS.…”

Section: Sudden Unexpected Infant and Perinatal Deathmentioning

confidence: 99%

Update on congenital heart disease and sudden infant/perinatal death: from history to future trends

Ottaviani

Buja

2017

J Clin Pathol

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During the 20th century, expert pathologists contributed an in-depth characterisation of the anatomical pathology and associated pathophysiology of congenital heart disease (CHD). Starting in the 1970s, the reported CHD birth prevalence has been increasing, owing to advances in diagnostic methods. Over the years, surgical treatments have been associated with an enormous reduction of CHD mortality. Advances also have been made in understanding the developmental biology and molecular pathogenesis of CHD. In developed countries, sudden infant death syndrome (SIDS) is the most frequent form of death during the first year of life, with a death rate of 0.42 every 1000 births. Unexpected stillbirth has a six- to eightfold greater incidence than that of SIDS and remains unexplained in 40-80% of cases even after autopsy. Specific environmental risk factors, such as maternal smoking, air and water pollution, food contamination, pesticides, etc, can interact with the genetic constitution in complex ways, which may lead to polymorphisms and/or mutations of specific genes, such as polymorphisms in the serotonin transporter gene , the regulator of the synaptic serotonin concentration. Current directions of research in this area are reviewed.

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“…4 L o s a u t o r e s d e f i n e n B R U E c o m o u n acontecimiento observado en niños menores de 1 año de edad, repentino y breve (de menos de un minuto de duración), resuelto en el momento de la consulta, caracterizado por al menos uno de los siguientes signos: cianosis o palidez, respiración irregular, ausente o disminuida, marcado cambio en el tono muscular (hiper-o hipotonía) o alteración del nivel de capacidad de respuesta.…”

Section: Brue: Un Nuevo Término Y Enfoque Que Podría Mejorar Nuestra unclassified

“…4 A partir de esta nueva definición, en los próximos meses se consensuarán nuevas guías o posturas prácticas tanto en las sociedades científicas como en los diversos ámbitos de asistencia para la aproximación al niño con dichos eventos. Este cambio nos acercará posiblemente a una medicina de mejor calidad, centrada en el niño y su familia, y que reduzca las intervenciones innecesarias y costosas.…”

Section: Brue: Un Nuevo Término Y Enfoque Que Podría Mejorar Nuestra unclassified

BRUE: Un nuevo término y enfoque que podría mejorar nuestra práctica

Rivarola

2016

Arch Argent Pediat

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Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower-Risk Infants: Executive Summary

Cited by 48 publications

References 5 publications

Desaturation During Cry in the Neonatal Period

Desaturation During Cry in the Neonatal Period

Update on congenital heart disease and sudden infant/perinatal death: from history to future trends

BRUE: Un nuevo término y enfoque que podría mejorar nuestra práctica

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