Brief Report: Implementation of a Specific Carbohydrate Diet for a Child with Autism Spectrum Disorder and Fragile X Syndrome

Barnhill, Kelly; Devlin, Morgan; Moreno, Hannah Taylor; Potts, Amy; Richardson, Wendy; Schutte, Claire; Hewitson, Laura

doi:10.1007/s10803-018-3704-9

Cited by 16 publications

(19 citation statements)

References 47 publications

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“…There is a paucity of studies examining the effects of diet in FXS [ 11 , 14 , 15 , 19 , 20 , 21 , 22 , 23 , 24 ]. Herein, diet-responsive autistic behaviors in FXS included three behaviors in girls within the Language category (talk, speak in 3-word sentences and use words to request things), one behavior in girls within the Parent Thought Problem category (learning problem), and one behavior in boys within the Autistic Behaviors category (injure self) in association with soy-based infant formula.…”

Section: Discussionmentioning

confidence: 99%

Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding

Westmark

2021

Nutrients

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This study evaluates the prevalence of autistic behaviors in fragile X syndrome as a function of infant diet. Retrospective survey data from the Fragile X Syndrome Nutrition Study, which included data on infant feeding and caregiver-reported developmental milestones for 190 children with fragile X syndrome enrolled in the Fragile X Online Registry with Accessible Database (FORWARD), were analyzed. Exploratory, sex-specific associations were found linking the use of soy-based infant formula with worse autistic behaviors related to language in females and self-injurious behavior in males. These findings prompt prospective evaluation of the effects of soy-based infant formula on disease comorbidities in fragile X syndrome, a rare disorder for which newborn screening could be implemented if there was an intervention. Gastrointestinal problems were the most common reason cited for switching to soy-based infant formula. Thus, these findings also support the study of early gastrointestinal problems in fragile X syndrome, which may underly the development and severity of disease comorbidities. In conjunction with comorbidity data from the previous analyses of the Fragile X Syndrome Nutrition Study, the findings indicate that premutation fragile X mothers should be encouraged to breastfeed.

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Section: Discussionmentioning

confidence: 99%

Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding

Westmark

2021

Nutrients

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“…The research design used in a number of studies was influenced by previous research conducted by the authors (Barnhill et al, 2018; Bird et al, 2011). This has the limitation that additional factors influencing the dependent variable in this specific population may have been missed.…”

Section: Critical Review Of the Literaturementioning

confidence: 99%

“…The only studies that measured the nutritional content of food consumed were Durand (1975) who recorded caloric intake and Searle (1994) who used serology and food/drink logs to ascertain caffeine intake. Two studies completed a comprehensive measure of nutritional intake (Barnhill et al, 2018; Bird et al, 2011), which included both validated assessment tools and objective markers, including laboratory analysis using serology. The data collection methods used by Barnhill et al (2018) included anthropometric, biochemical analysis, clinical symptoms, dietary assessment and environmental assessment in line with the ABCDE approach to nutritional assessment.…”

Section: Critical Review Of the Literaturementioning

confidence: 99%

The impact of nutrition on sleep in people with an intellectual disability: An integrative literature review

Harper

Ooms

Wijne

2021

Research Intellect Disabil

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Background People with intellectual disabilities are more likely to experience sleep problems. Sleep can impact on health and well‐being; therefore, evidence‐based interventions are required to improve sleep in this population. Method An integrative literature review was conducted on the impact of nutrition on sleep in people with intellectual disabilities. Following screening of papers (n = 289), 14 papers met the inclusion criteria. Results Themes related to nutrition and improved overall well‐being, use of nutritional supplements, specific foods, links to health comorbidities and food fussiness. Conclusion This is the first comprehensive review completed on nutritional interventions to improve sleep in people with intellectual disabilities. Dietary patterns may be an important factor to improving the quality and quantity of sleep. However, the current literature regarding the benefit of improved nutrition on sleep in people with an intellectual disability needs to be interpreted with caution.

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“…Os pacientes com TEA cursam com maior prevalência de SGI se comparados com aqueles com desenvolvimento típico, sendo ainda associados com a severidade do autismo 23 . Esse aumento nos distúrbios GI pode estar ligado a diversos mecanismos, como uma disbiose frequentemente associada a um aumento da permeabilidade intestinal, permitindo a passagem de metabólitos bacterianos que podem afetar o sistema nervoso central 43,44 .…”

Section: Tea E Permeabilidade Intestinalunclassified

Carboidratos fermentáveis: estudo de revisão e análise da relação com transtorno do espectro autista

Hobus

Ramos

Monk

et al. 2021

SDH

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Objetivo: reunir informações sobre o efeito da dieta com baixo teor de carboidratos fermentáveis sobre sintomas gastrointestinais, assim como sua aplicação nos transtornos do espectro autista.Método: revisão sistemática de literatura, utilizando-se descritores em inglês e português, das bases de dados Biblioteca Nacional de Medicina dos Estados Unidos, Biblioteca Virtual da Saúde e Portal de Periódicos Capes.Resultados: encontrou-se 33 artigos, dos quais dois eram coorte, 10 transversais, nove caso-controle e 12 ensaios clínicos. Os objetivos foram investigar a melhora dos sintomas gastrointestinais a partir da dieta com baixo teor de FODMAPs em pacientes com Síndrome do Intestino Irritável e Doença Inflamatória Intestinal. Na população com transtorno do espectro autista os objetivos foram avaliar a incidência de sintomas gastrointestinais e o impacto da restrição de FODMAPs nos mesmos. Os estudos mostraram melhoras de sintomas gastrointestinais, com alívio após implementação da dieta, em especial em pacientes com síndrome do intestino inflamatório e doença inflamatória intestinal.Conclusões: a dieta com baixo teor de FODMAPs mostrou melhora de sintomas gastrointestinais quando aplicada a indivíduos com alterações intestinais. Contudo são necessárias maiores evidências cientificas para indicar sua aplicação como medida de rotina no transtorno do espectro autista.

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Brief Report: Implementation of a Specific Carbohydrate Diet for a Child with Autism Spectrum Disorder and Fragile X Syndrome

Cited by 16 publications

References 47 publications

Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding

Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding

The impact of nutrition on sleep in people with an intellectual disability: An integrative literature review

Carboidratos fermentáveis: estudo de revisão e análise da relação com transtorno do espectro autista

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