Brief Report: Estimated Incidence of Perinatally Acquired HIV Infection in the United States, 1978–2013

Nesheim, Steven; Wiener, Jeffrey; Harris, Lauren; Lampe, Margaret A.; Weidle, Paul J.

doi:10.1097/qai.0000000000001552

Cited by 24 publications

(18 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1,2 An elevated viral load increases the risk of perinatal transmission of HIV and can lead to maternal progression to AIDS. Although the United States is reaching elimination goals for perinatal transmission of HIV, 3 racial disparities persist with perinatal transmission being 10 times higher among blacks compared to Hispanics and whites. 4 Poor retention in HIV care postpartum can lead to poor maternal health and can compromise pediatric health.…”

Section: Introductionmentioning

confidence: 99%

Assessing the Acceptability of a Peer Mentor Mother Intervention to Improve Retention in Care of Postpartum Women Living with HIV

et al. 2019

View full text Add to dashboard Cite

Background: Many women living with HIV (WLWH) experience poor postpartum retention in HIV care. There are limited evidence-based interventions in the United States aimed at increasing retention of WLWH postpartum; however, evidence from low-resource settings suggest that women who receive peer mentoring experience higher retention and viral suppression postpartum. Methods: We conducted 15 semistructured interviews with pregnant or postpartum women from an urban U.S. clinic to assess factors influencing maternal adherence to antiretroviral therapy (ART) and retention in HIV care. We then assessed the acceptability of a peer intervention in mitigating barriers to sustain adherence and retention in care postpartum. Interviews were audio taped, transcribed, and analyzed. Codes were developed and applied to all transcripts, and matrices were used to facilitate comparisons across different types of participants. Results: Participants included low-income black and Hispanic women with a mean age of 31 years (range 22–42). Social support and concern for infants' well-being were strong facilitators for engaging in care. Psychosocial challenges, such as stigma and isolation, fear of disclosure, and depression, negatively influenced adherence to ART and engagement in care. Regardless of their level of adherence to ART, women felt that peer mentoring would be an acceptable intervention to reinforce skill-related ART adherence and sustain engagement in care after delivery. Conclusion: A peer mentor mother program is a promising intervention that can improve the care continuum of pregnant and postpartum women in the United States. Messaging that maximizes maternal support and women's motivation to keep their infant healthy may leverage retention in care postpartum.

show abstract

Section: Introductionmentioning

confidence: 99%

Assessing the Acceptability of a Peer Mentor Mother Intervention to Improve Retention in Care of Postpartum Women Living with HIV

et al. 2019

View full text Add to dashboard Cite

show abstract

“…In our study, the HIV MTCT rate in exposed children born in 2015 in Goiás and being followed in HDT was of 4.34%. This rate is lower compared to certain rates of other Brazilian regions, such as the 6.6% rate found in a cohort study performed in the state of Amazonas between 1999 and 2011 11 , and also lower than some developed countries' rates, such as the 6% rate found in a cohort study performed in the University of Texas from 2000 to 2007 7 -as in the United States the estimated incidence of perinatal HIV infection in 2013 was of 1.8 per thousand inhabitants, with a 96% decrease in the HIV MTCT rate between 1992 and 2013 12 .…”

Section: Discussionmentioning

confidence: 61%

Análise da taxa de transmissão vertical do HIV e fatores de risco materno-fetais em crianças expostas nascidas em centro de referência do estado de Goiás

Rosa

Albuquerque

Filho

et al. 2021

Rev. Med. (São Paulo)

View full text Add to dashboard Cite

Objetivos: Estimar a taxa de transmissão vertical do HIV e os fatores de risco materno-fetais em crianças nascidas em 2015 em seguimento durante os anos de 2015 a 2017 no maior centro de referência para tratamento para HIV do estado de Goiás. Métodos: Estudo de coorte retrospectivo de 111 crianças expostas ao HIV nascidas em 2015 de mães HIV positivas. Resultados: Entre as mães, 85 (92,4%) utilizaram TARV durante a gestação. Das 92 crianças que mantiveram seguimento, 4 (4,34%) adquiriram infecção perinatal pelo HIV. 81 (88%) recém-nascidos fizeram uso de profilaxia antirretroviral. Um fator protetor importante de transmissão vertical do HIV foi a profilaxia antirretroviral do RN (OR = 0,02; IC 95%: 0,00-0,56; p = 0,04). Outros fatores investigados, como uso de TARV durante a gestação, não foram estatisticamente significativas para risco. Conclusão: A taxa de transmissão vertical do HIV ainda se encontra elevada no estado de Goiás e os desafios para sua prevenção consistem na perda de seguimento e falhas nas medidas estratégicas.

show abstract

“…2 Perinatal HIV transmission has decreased substantially since its peak in 1992. 6 There were 99 diagnoses of perinatally acquired HIV infection in 2016, 2 and approximately 8700 women living with HIV give birth each year. 5 There are racial/ethnic disparities in rates of perinatally acquired HIV infection; rates are 5 times greater in black/African American women than in white or Hispanic/Latino women.…”

Section: Burden Of Diseasementioning

confidence: 99%

Screening for HIV Infection

Force

Owens

Davidson

et al. 2019

JAMA

146

View full text Add to dashboard Cite

IMPORTANCE Approximately 1.1 million persons in the United States are currently living with HIV, and more than 700 000 persons have died of AIDS since the first cases were reported in 1981. There were approximately 38 300 new diagnoses of HIV infection in 2017. The estimated prevalence of HIV infection among persons 13 years and older in the United States is 0.4%, and data from the Centers for Disease Control and Prevention show a significant increase in HIV diagnoses starting at age 15 years. An estimated 8700 women living with HIV give birth each year in the United States. HIV can be transmitted from mother to child during pregnancy, labor, delivery, and breastfeeding. The incidence of perinatal HIV infection in the United States peaked in 1992 and has declined significantly following the implementation of routine prenatal HIV screening and the use of effective therapies and precautions to prevent mother-to-child transmission. OBJECTIVE To update the 2013 US Preventive Services Task Force (USPSTF) recommendation on screening for HIV infection in adolescents, adults, and pregnant women. EVIDENCE REVIEW The USPSTF reviewed the evidence on the benefits and harms of screening for HIV infection in nonpregnant adolescents and adults, the yield of screening for HIV infection at different intervals, the effects of initiating antiretroviral therapy (ART) at a higher vs lower CD4 cell count, and the longer-term harms associated with currently recommended ART regimens. The USPSTF also reviewed the evidence on the benefits (specifically, reduced risk of mother-to-child transmission of HIV infection) and harms of screening for HIV infection in pregnant persons, the yield of repeat screening for HIV at different intervals during pregnancy, the effectiveness of currently recommended ART regimens for reducing mother-to-child transmission of HIV infection, and the harms of ART during pregnancy to the mother and infant. FINDINGS The USPSTF found convincing evidence that currently recommended HIV tests are highly accurate in diagnosing HIV infection. The USPSTF found convincing evidence that identification and early treatment of HIV infection is of substantial benefit in reducing the risk of AIDS-related events or death. The USPSTF found convincing evidence that the use of ART is of substantial benefit in decreasing the risk of HIV transmission to uninfected sex partners. The USPSTF also found convincing evidence that identification and treatment of pregnant women living with HIV infection is of substantial benefit in reducing the rate of mother-to-child transmission. The USPSTF found adequate evidence that ART is associated with some harms, including neuropsychiatric, renal, and hepatic harms, and an increased risk of preterm birth in pregnant women. The USPSTF concludes with high certainty that the net benefit of screening for HIV infection in adolescents, adults, and pregnant women is substantial. CONCLUSIONS AND RECOMMENDATION The USPSTF recommends screening for HIV infection in adolescents and adults aged 15 to 65 years. You...

show abstract

Brief Report: Estimated Incidence of Perinatally Acquired HIV Infection in the United States, 1978–2013

Cited by 24 publications

References 16 publications

Assessing the Acceptability of a Peer Mentor Mother Intervention to Improve Retention in Care of Postpartum Women Living with HIV

Assessing the Acceptability of a Peer Mentor Mother Intervention to Improve Retention in Care of Postpartum Women Living with HIV

Análise da taxa de transmissão vertical do HIV e fatores de risco materno-fetais em crianças expostas nascidas em centro de referência do estado de Goiás

Screening for HIV Infection

Contact Info

Product

Resources

About