Brief Descriptive Epidemiology of Primary Malignant Brain Tumors from North-East India

Abstract

Brain tumors are a mixed group of neoplasms that originate from the intracranial tissues and the meninges with degrees of malignancy varying greatly from benign to aggressive. Not much is known about the epidemiology of primary malignant brain tumors (PMBTs) in our population in North-East India. In this analysis, an attempt was made to identify the age groups, gender distribution, topography and different histological types of PMBT with data from a hospital cancer registry. A total of 231 cases of PMBT were identified and included for the present analysis. Our analysis has shown that most of PMBT occur at 20-60 years of age, with a male to female ratio of 2.3:1. Some 70.5% of cases occurred in cerebral lobes except for the occipital lobe, and astrocytic tumors were the most common broad histological type. In our population the prevalence of PMBT is 1% of all cancers, mostly affecting young and middle aged patients. As brain tumors are rare, so case-control analytic epidemiological studies will be required to establish the risk factors prevalent in our population.

Histopathological analysis of central nervous system tumor; an observational study

“…The age group of patients with CNS tumors also corroborated with studies like that of Krishnatreya M et al in which the highest number of patients was seen in the age-group of 20-39 years and 21-40 years in our study. 12…”

A ocorrência de tumores do sistema nervoso central no estado de Sergipe no período de 2008 a 2017

“…Para estes autores, a ocorrência de tumores cerebrais primários malignos entre os adultos foi de 65% e de 33% em crianças. Krishnatreya et al, 2014, na Índia, relataram que a maioria dos tumores ocorreu em adultos, entre 20 e 60 anos de idade (Krishnatreya et al, 2014 (Japan, 2017).…”

“…aproximadamente 75% dos tumores primários de cérebro são classificados em gliomas e meningiomas (Fisher et al, 2007). Krishnatreya et al, 2014 na Índia, analisando, os principais subtipos histológicos, de tumores cerebrais em 231 casos, relataram a ocorrência do: astrocitoma difuso em 37,2% (86), glioblastoma multiforme, 21,2% (49) glioma astrocítico, 10,3% (24), meduloblastoma, 9,5% (22) e o oligodendroglioma em 6,4% (15) dos pacientes (Krishnatreya et al, 2014). Um estudo epidemiológico de uma série de tumores primários do SNC realizado na cidade de Porto Alegre, foram encontrados 39 tipos de tumores.…”

“…Shibui et al (2014) descreveram que 29% dos casos estavam localizados no hemisfério direito, 30% no esquerdo, e que 8% dos casos englobaram ambos hemisférios (Shibui, 2014). Na Índia, Krishnatreya et al (2014) relataram como principal localização de tumor cerebral o lobo frontal (44,6%), seguido pelos lobos parietal (13,4%) e temporal (12,5%) (Krishnatreya et al, 2014). Larjavaara et al (2007) na Finlândia, demonstraram diferenças consideráveis na Research, Society and Development, v. 9, n. 11, e3439119673, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i11.9673 distribuição de gliomas, com maior ocorrência no lobo frontal (32,3%) e maior frequência no hemisfério direito (51%) e hemisfério esquerdo (40%) (Larjavaara et al, 2007).…”

“…mulheres de 2,3:1(Krishnatreya et al, 2014). Enquanto para Sanchez & Alfonso (2010) foi de 60% dos casos, para o sexo masculino.…”