Bridging the Gap: Racial concordance as a strategy to increase African American participation in breast cancer research

Frierson, Georita Marie; Pinto, Bernardine M.; Denman, Deanna C.; Leon, Pierre A; Jaffe, Alex D

doi:10.1177/1359105317740736

Cited by 29 publications

(25 citation statements)

References 32 publications

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“…Previous studies have found racial concordance (between researcher and participant) to be a predictor of willingness to participate (Frierson et al 2019). Our findings add that both the institutional affiliation and the racial identity of the researcher can act as heuristics or shortcuts in the decision-making process, representing trustworthiness.…”

Section: Resultsmentioning

confidence: 99%

“…Our choice of the four dimensions used in research scenarios was informed by previous research. The researcher’s race was included to explore the relative weight of racial/ethnic concordance, which is a known facilitator of trust in research and health care (Frierson et al 2019; Fryer et al 2015; Shen et al 2018). The research goal was included to explore the power of altruism in willingness to participate in research (Chin et al 2016; Hughes et al 2015; Ojukwu et al 2018).…”

Section: Choice Of Scenario Characteristicsmentioning

confidence: 99%

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Use of a Qualitative Story Deck to Create Scenarios and Uncover Factors Associated with African American Participation in Genomics Research

et al. 2020

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To explore the willingness to participate in genomics research among African Americans, we developed a technique specifically suited to a relaxed social setting. The “Qualitative Story Deck,” (QSD) is a gamified, structured elicitation technique that allows for the spontaneous creation of scenarios with variable attributes. We used the QSD to create research scenarios that varied on four details (race/ethnicity of the researcher, research goal, biospecimen requested, and institutional affiliation). Participants created scenarios by randomly choosing cards from these categories and provided: (1) a judgment about their willingness to participate in the research project represented; and (2) their thought process in reaching a decision. The QSD has applicability to topics involving decision making or in cases where it would be beneficial to provide vignettes with alternate attributes. Additional benefits include rapid rapport building, applicability to little known or sensitive topics, and suitability for both qualitative and quantitative analyses.

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Section: Resultsmentioning

confidence: 99%

Section: Choice Of Scenario Characteristicsmentioning

confidence: 99%

Use of a Qualitative Story Deck to Create Scenarios and Uncover Factors Associated with African American Participation in Genomics Research

et al. 2020

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“…Previous studies have shown that racial concordance is a potential facilitator to recruiting AA populations. 43,44 Hence, our partnership with UAB’s RRSF and their racially diverse team of recruiters may have contributed to ENABLE CHF-PC’s successful recruitment of a high proportion of AAs.…”

Section: Discussionmentioning

confidence: 99%

African American Recruitment in Early Heart Failure Palliative Care Trials: Outcomes and Comparison With the ENABLE CHF-PC Randomized Trial

et al. 2020

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Background: Palliative care trial recruitment of African Americans (AAs) is a formidable research challenge. Objectives: Examine AA clinical trial recruitment and enrollment in a palliative care randomized controlled trial (RCT) for heart failure (HF) patients and compare patient baseline characteristics to other HF palliative care RCTs. Methods: This is a descriptive analysis the ENABLE CHF-PC (Educate, Nurture, Advise, Before Life Ends: Comprehensive Heartcare for Patients and Caregivers) RCT using bivariate statistics to compare racial and patient characteristics and differences through recruitment stages. We then compared the baseline sample characteristics among three palliative HF trials. Results: Of 785 patients screened, 566 eligible patients with NYHA classification III-IV were approached; 461 were enrolled and 415 randomized (AA = 226). African Americans were more likely to consent than Caucasians (55%; P FDR = .001), were younger (62.7 + 8; P FDR = .03), had a lower ejection fraction (39.1 + 15.4; PFDR = .03), were more likely to be single ( P FDR = .001), and lack an advanced directive (16.4%; P FDR < .001). AAs reported higher goal setting (3.3 + 1.3; P FDR = .007), care coordination (2.8 + 1.3; P FDR = .001) and used more “denial” coping strategies (0.8 + 1; P FDR = .001). Compared to two recent HF RCTs, the ENABLE CHF-PC sample had a higher proportion of AAs and higher baseline KCCQ clinical summary scores. Conclusion: ENABLE CHF-PC has the highest reported recruitment rate and proportion of AAs in a palliative clinical trial to date. Community-based recruitment partnerships, recruiter training, ongoing communication with recruiters and clinician co-investigators, and recruiter racial concordance likely contributed to successful recruitment of AAs. These important insights provide guidance for design of future HF palliative RCTs. Trial Registration: ClinicalTrials.gov Identifier: NCT02505425

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“…Racial and cultural concordance between research staff and participants, including the use of investigators and staff from the same targeted communities as participants, and partnerships with community organizations, can all facilitate greater inclusivity and increased REMG recruitment 29,30,43. Lack of diversity among gynecologic oncology providers challenges the use of racially and culturally concordant investigators and practices.…”

Section: Contributing Factorsmentioning

confidence: 99%

Enrollment of Racial and Ethnic Minoritized Groups in Gynecologic Oncology Clinical Trials: A Review of the Scope of the Problem, Contributing Factors, and Strategies to Improve Inclusion

Barry¹,

Steinberg²,

Towner

et al. 2022

Clinical Obstetrics &Amp; Gynecology

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Racial inequities are well-documented across the gynecologic oncology care continuum, including the representation of racial and ethnic minoritized groups (REMGs) in gynecologic oncology clinical trials. We specifically reviewed the scope of REMG disparities, contributing factors, and strategies to improve inclusion. We found systematic and progressively worsening under-enrollment of REMGs, particularly of Black and Latinx populations. In addition, race/ethnicity data reporting is poor, yet a prerequisite for accountability to recruitment goals. Trial participation barriers are multifactorial, and successful remediation likely requires multi-level strategies. More rigorous, transparent data on trial participants and effectiveness studies on REMG recruitment strategies are needed to improve enrollment.

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Bridging the Gap: Racial concordance as a strategy to increase African American participation in breast cancer research

Cited by 29 publications

References 32 publications

Use of a Qualitative Story Deck to Create Scenarios and Uncover Factors Associated with African American Participation in Genomics Research

Use of a Qualitative Story Deck to Create Scenarios and Uncover Factors Associated with African American Participation in Genomics Research

African American Recruitment in Early Heart Failure Palliative Care Trials: Outcomes and Comparison With the ENABLE CHF-PC Randomized Trial

Enrollment of Racial and Ethnic Minoritized Groups in Gynecologic Oncology Clinical Trials: A Review of the Scope of the Problem, Contributing Factors, and Strategies to Improve Inclusion

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