Bridging Histopathology and Radiomics Toward Prognosis of Metastasis in Early Breast Cancer
Marko Radulović,
Xingyu Li,
Goran J Djuričić
et al.
Abstract:Tumor histomorphology is crucial for the prognostication of breast cancer outcomes because it contains histological, cellular, and molecular tumor heterogeneity related to metastatic potential. To enhance breast cancer prognosis, we aimed to apply radiomics analysis—traditionally used in 3D scans—to 2D histopathology slides. This study tested radiomics analysis in a cohort of 92 breast tumor specimens for outcome prognosis, addressing -omics dimensionality by comparing models with moderate and high feature cou… Show more
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