Bremsstrahlung dose of therapeutic beta nuclides in bone and muscle

Abstract

In the nuclear medicine, beta nuclides are released during the treatment. This beta interacts with bone and muscle and produces external Bremsstrahlung (EB) radiation. Present work formulated a new method to evaluate the EB spectrum and hence the Bremsstrahlung dose of therapeutic beta nuclides (Lu-177, Sr-90, Sm-153, I-153, Cs-137, Au-201, Dy-165, Mo-99, Sr-89, Fe-59, P-32, Ho-166, Sr-92, Re-188, Y-90, Pr-147, Co-60, K-42) in bone and muscle. The Bremsstrahlung yields of these beta nuclides are also estimated. Bremsstrahlung production is higher in bone than that of muscle. Presented data provides a quick and convenient reference for radiation protection and it can be quickly employed to give a first pass dose estimate prior to a more detailed experimental study.

Bremsstrahlung dose of 165Dy in radiosynovectomy

“…Local instillation of radiopharmaceuticals can reduce effusion (9) . In our previous work, (10) we have formulated a general method to evaluate the EB spectrum and hence the bremsstrahlung dose of therapeutic beta nuclides in bone and muscle only. Radiation therapy needs experimental studies on the exposure due to bremsstrahlung in tissues.…”