Breeding of Hypoallergenic Fruits

Gilissen, L.J.W.J.

doi:10.1002/9780470959350.ch5

Cited by 2 publications

(1 citation statement)

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“…The fact that its putative encoding gene is abundantly expressed during bayberry fruit ripening (unpublished data) warrants further studies into a possible role for a TLP in the bayberry fruit allergy. With preliminary skin prick tests showing possible allergenicity differences among Chinese bayberry cultivars (Table 1), further in vitro and in vivo testings with more patients and cultivars are planned to select hypoallergenic cultivars using similar approaches to that used in apple (Gao and Gilissen, 2011).…”

Section: Discussionmentioning

confidence: 99%

Anaphylaxis and generalized urticaria from eating Chinese bayberry fruit

Wang

Yang

Shao

et al. 2012

J. Zhejiang Univ. Sci. B

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Chinese bayberry Myrica rubra is a very popular fruit in southeastern China. In spite of its wide consumption, no allergies to this fruit have been reported previously. Here we report on a 40-year-old woman suffering from anaphylaxis to Chinese bayberry fruit. Prick-prick skin tests revealed strong reactions to fresh Chinese bayberry fruits as well as to peach, and weaker reactions to some other fruits including apple, melon, and banana. ImmunoCAP analysis revealed identical titers of specific IgE (4.3 kU(A)/L) to peach extract and its lipid transfer protein (LTP, rPru p 3), which was confirmed by detection of a 9 kD band following immunoblotting. Immunoblot analysis with Chinese bayberry extract gave bands of 22, 45, and 90 kD, but no 9 kD band was recognized. There was also no evidence of LTP recognition for loquat (36 kD) or melon (24 kD). This first report of a severe allergic reaction to Chinese bayberry fruit in a patient with LTP-mediated peach allergy indicates that other as yet unidentified non-pollen related fruit allergens are involved in this new severe fruit allergy.

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Section: Discussionmentioning

confidence: 99%