Breed‐associated phenotypes in canine atopic dermatitis

Wilhem, Sylvia; Kovalik, Marcel; Favrot, Claude

doi:10.1111/j.1365-3164.2010.00925.x

Cited by 73 publications

(86 citation statements)

References 5 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No differences were found between the groups regarding the presence of respiratory signs and conjunctivitis, which were infrequent in our canine patients. Conjunctivitis was observed in 18.6% of all enrolled dogs and similar results have been reported elsewhere . In another study, the frequency of allergic conjunctivitis in atopic dogs was 60%, suggesting that conjunctivitis could in fact be underdiagnosed in this disease …”

Section: Discussionsupporting

confidence: 87%

Comparison of demographic data, disease severity and response to treatment, between dogs with atopic dermatitis and atopic‐like dermatitis: a retrospective study

Botoni

Torres

Koch

et al. 2018

Veterinary Dermatology

View full text Add to dashboard Cite

Background Limited information is available describing the features of canine atopic‐like dermatitis (ALD) compared with atopic dermatitis (AD). Objectives To compare demographic data, disease severity and response to therapy between ALD and AD dogs. Animals Two hundred and fifty‐three atopic dogs with intradermal and serum allergen‐specific IgE test results were selected retrospectively. Methods and materials Dogs were enrolled into the ALD group if both IgE tests were negative and into the AD group if at least one test was positive. Demographic data, pruritus level and number of body sites affected before and during therapy, in addition to maintenance therapy protocols, were compared between groups. Results There were 216 (85.38%) dogs in the AD group and 37 (14.62%) in the ALD group. The soft‐coated wheaten terrier, American Staffordshire terrier, English bulldog and Labrador retriever were over‐represented in the AD group. No significant differences between the groups were noted regarding the other demographic variables evaluated. There were no differences in the mean pruritus scores and number of affected body sites at the first visit or during treatment. Furthermore, no significant differences between the groups were noted for the maintenance treatment scores and reduction of pruritus level and number of body sites affected during treatment. Conclusions and clinical significance The soft‐coated wheaten terrier, American Staffordshire terrier, English bulldog and Labrador retriever were over‐represented in the AD group. No significant differences in the other demographic data and clinical features were noted between dogs with ALD and AD in the present study.

show abstract

Section: Discussionsupporting

confidence: 87%

Comparison of demographic data, disease severity and response to treatment, between dogs with atopic dermatitis and atopic‐like dermatitis: a retrospective study

Botoni

Torres

Koch

et al. 2018

Veterinary Dermatology

View full text Add to dashboard Cite

show abstract

“…This prevalence is in the range found in previous studies that had included dogs from many breeds . In one report where the WHWT had been studied separately, the prevalence of FIAD was 23%, a proportion identical to the one found herein …”

Section: Discussionsupporting

confidence: 82%

Atopic dermatitis in West Highland white terriers – part I: natural history of atopic dermatitis in the first three years of life

Favrot

Fischer

Olivry

et al. 2019

Veterinary Dermatology

Self Cite

View full text Add to dashboard Cite

Background Canine atopic dermatitis (cAD) is a common allergic skin disease that is known to affect individuals early in life; the natural history of its initial development has not been documented. Some breeds such as West Highland white terriers (WHWTs) are highly predisposed to cAD. Objectives To follow 100 WHWT puppies during their first three years and to record the onset of clinical signs of cAD. Animals One hundred and eight puppies from 29 litters were included and 90 were followed for three years. Methods and materials Puppies were examined initially while with their breeders. After adoption, the owners were contacted twice each year and dogs were examined by veterinarians if signs compatible with cAD were detected; diagnosis of cAD was by two different definitions. The onset, location of the clinical signs and severity of cAD, as well as co‐morbidities were recorded. Results The prevalence of cAD in the cohort was 52%. Most affected dogs (60%) developed signs of cAD during their first year of life and males were over‐represented. The location of clinical signs mirrored those of previous descriptions. The severity of cAD was mild in 36% and severe in 13% of affected WHWTs. Dogs with cAD often exhibited other atopic diseases, but only gastro‐intestinal signs were significantly different between WHWTs with and without cAD. Adverse reaction to foods was diagnosed in 24% of dogs. Conclusion and clinical importance This longitudinal study of puppies from a predisposed breed sheds new light on the early development of cAD in WHWTs.

show abstract

“…Our data did not show any associations between breeds and the distribution of the other lesions of CAD, however, such associations have been reported (Picco et al 2008;Jaeger et al 2010;Wilhem et al 2011). The clinical significance of these findings is unclear, however, and none of these associations was included in the new criteria for the diagnosis of CAD (Favrot et al 2010).…”

Section: Lesions Of Dogs With Cadcontrasting

confidence: 40%

“…In a survey on dogs with CAD from three continents, Beagles, French Bulldogs, GSDs and Jack Russell terriers with otitis externa were presented significantly more (Jaeger et al 2010). In another recent study boxers were reported to be highly affected with otitis (Wilhem et al 2011).…”

Section: Lesions Of Dogs With Cadmentioning

confidence: 99%

Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

Zur¹,

Skorinsky²,

Bdolah‐Abram³

2012

Vet. Med. - Czech

View full text Add to dashboard Cite

ABSTRACT:The aim of the study was to examine for the first time the various aspects of canine atopic dermatitis (CAD) presenting in a Middle Eastern country. Medical records of 164 dogs diagnosed with CAD were evaluated. Associations between signalment, lifestyle, clinical signs and allergens were evaluated statistically. Labrador Retriever, German Shepherd dog, Boxer, French Bulldog, Golden Retriever and Shar-Pei breeds were presented more frequently than the regular hospital population (P < 0.0001), and had an earlier disease onset time (P < 0.01). In 22 dogs (13%) signs of CAD were noticed at less than six months of age. Most dogs (75%) lived indoors. Most dogs (83%) had lesions on the ventral part of the body and 68% had foot lesions. After excluding flea allergy dermatitis by implementing strict flea control, 60% of the dogs presented with dorsal distribution of skin lesions. Dogs with ventral lesions were younger when clinical signs first appeared (P < 0.05). Most of the dogs were allergic to dust and/or dust mites (75.6%), with weeds and trees as the next most common allergens. CAD is similar worldwide, but geographic differences may be attributable to genetic pools and allergen loading. This study also shows that early onset of clinical signs, especially in breeds predisposed to CAD and with a dorsal distribution of skin lesions, should not rule out the diagnosis of CAD.

show abstract

Breed‐associated phenotypes in canine atopic dermatitis

Cited by 73 publications

References 5 publications

Comparison of demographic data, disease severity and response to treatment, between dogs with atopic dermatitis and atopic‐like dermatitis: a retrospective study

Comparison of demographic data, disease severity and response to treatment, between dogs with atopic dermatitis and atopic‐like dermatitis: a retrospective study

Atopic dermatitis in West Highland white terriers – part I: natural history of atopic dermatitis in the first three years of life

Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

Contact Info

Product

Resources

About