Breathless nights and heart flutters: Understanding the relationship between obstructive sleep apnea and atrial fibrillation

Mills, Eric W; Antman, Elliott M.; Javaheri, Sogol

doi:10.1016/j.hrthm.2023.04.022

Cited by 6 publications

(4 citation statements)

References 101 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This suggests that in addition to the mechanism of altered cardiac structure promoting AF, OSA also involves other mechanisms that promote the occurrence and progression of AF, such as endothelial system dysfunction, inflammatory response, and oxidative stress. 15…”

Section: Discussionmentioning

confidence: 99%

“…The copyright holder for this this version posted October 24, 2023. ; https://doi.org/10.1101/2023.10.17.23297177 doi: medRxiv preprint mechanisms that promote the occurrence and progression of AF, such as endothelial system dysfunction, inflammatory response, and oxidative stress. 15 While polysomnography remains the primary diagnostic method for OSA, the user-friendly Berlin questionnaire has emerged as a significant adjunct in clinical practice. In an earlier meta-analysis, Chee Yuan Ng et al discovered the Berlin questionnaire effectively identifies the risk of recurrence of AF (AF) in patients with OSA following PVI.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Impact of Continuous Positive Airway Pressure Therapy on the Recurrence of Atrial Fibrillation in Patients with Obstructive Sleep Apnea after pulmonary vein isolation

Fan,

Sun,

Cao

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Despite the recognized risk of atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) in patients with obstructive sleep apnea (OSA), the effect of continuous positive airway pressure (CPAP) remains inconsistent across studies, necessitating further examination. Methods: Utilizing databases encompassing Web of Science, Pubmed and OVID, we implemented a meta-analysis dedicated to investigating the role of OSA in post-PVI AF recurrence and the preventative properties of CPAP. Results: Our meta-analysis of OSA patients undergoing PVI suggests an AF recurrence risk with a RR (risk ratio) of 1.67 (95% CI: 1.52-1.83). For patients with no atrial size difference, the risk is RR=2.13 (95% CI: 1.63-2.79), and with size difference, it's RR=1.78 (95% CI: 1.46-2.17). Diagnoses from the Berlin questionnaire and polysomnography yielded RRs of 1.71 (95% CI: 1.37-2.14) and 1.75 (95% CI: 1.40-2.18), respectively. Non-CPAP usage increases AF recurrence risk by 67% and especially in cases of significant atrial size difference (RR=1.63, 95%CI:1.32-2.03). Conversely, when atrial size difference is absent, the impact of CPAP appears to be insignificant (RR=1.22, 95%CI: 0.98-3.02). Co-existence of paroxysmal and non-paroxysmal AF indicates a significant CPAP effect (RR=1.78, 95% CI: 1.50-2.09), contrary to one study on paroxysmal AF patients (RR=1.3, 95%CI: 0.71-1.50). Conclusion: Our meta-analysis found a significant risk of AF recurrence in patients with OSA following PVI. However, OSA had an insignificant impact on AF recurrence in paroxysmal AF patients. Non-CPAP usage generally increased recurrence risk. Yet, in subgroups without prominent atrial size difference and paroxysmal AF, CPAP's influence was not significant.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The Impact of Continuous Positive Airway Pressure Therapy on the Recurrence of Atrial Fibrillation in Patients with Obstructive Sleep Apnea after pulmonary vein isolation

Fan,

Sun,

Cao

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…[378] Obstructive sleep apnea affects the success rate of electrical cardioversion, catheter ablation, and the efficacy of antiarrhythmic drugs in AF patients. [379,380] However, evidence from RCTs suggests that continuous positive…”

Section: Obstructive Sleep Apnea Syndromementioning

confidence: 99%

Chinese Guidelines for the Diagnosis and Management of Atrial Fibrillation

MA,

WU,

LIU

et al. 2024

Journal of Geriatric Cardiology

View full text Add to dashboard Cite

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, significantly impacting patients' quality of life and increasing the risk of death, stroke, heart failure, and dementia. Over the past two decades, there have been significant breakthroughs in AF risk prediction and screening, stroke prevention, rhythm control, catheter ablation, and integrated management. During this period, the scale, quality, and experience of AF management in China have greatly improved, providing a solid foundation for the development of guidelines for the diagnosis and management of AF. To further promote standardized AF management, and apply new technologies and concepts to clinical practice in a timely and comprehensive manner, the Chinese Society of Cardiology of the Chinese Medical Association and the Heart Rhythm Committee of the Chinese Society of Biomedical Engineering have jointly developed the Chinese Guidelines for the Diagnosis and Management of Atrial Fibrillation. The guidelines have comprehensively elaborated on various aspects of AF management and proposed the CHA 2 DS 2 -VASc-60 stroke risk score based on the characteristics of AF in the Asian population. The guidelines have also reevaluated the clinical application of AF screening, emphasized the significance of early rhythm control, and highlighted the central role of catheter ablation in rhythm control.

show abstract

“…379,380 However, evidence from RCTs suggests that continuous positive airway pressure therapy does not reduce AF burden or increase the success rate of catheter ablation. 381 The management of risk factors for AF is summarized in Table 45.…”

Section: Obstructive Sleep Apnea Syndromementioning

confidence: 99%

Chinese guidelines for the diagnosis and management of atrial fibrillation

Ma,

Wu,

Liu

et al. 2024

Pacing Clinical Electrophis

View full text Add to dashboard Cite

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, significantly impacting patients' quality of life and increasing the risk of death, stroke, heart failure, and dementia. Over the past two decades, there have been significant breakthroughs in AF risk prediction and screening, stroke prevention, rhythm control, catheter ablation, and integrated management. During this period, the scale, quality, and experience of AF management in China have greatly improved, providing a solid foundation for the development of the guidelines for the diagnosis and management of AF. To further promote standardized AF management, and apply new technologies and concepts to clinical practice timely and fully, the Chinese Society of Cardiology of Chinese Medical Association and the Heart Rhythm Committee of Chinese Society of Biomedical Engineering jointly developed the Chinese Guidelines for the Diagnosis and Management of Atrial Fibrillation. The guidelines comprehensively elaborated on various aspects of AF management and proposed the CHA2DS2‑VASc‑60 stroke risk score based on the characteristics of the Asian AF population. The guidelines also reevaluated the clinical application of AF screening, emphasized the significance of early rhythm control, and highlighted the central role of catheter ablation in rhythm control.

show abstract

Breathless nights and heart flutters: Understanding the relationship between obstructive sleep apnea and atrial fibrillation

Cited by 6 publications

References 101 publications

The Impact of Continuous Positive Airway Pressure Therapy on the Recurrence of Atrial Fibrillation in Patients with Obstructive Sleep Apnea after pulmonary vein isolation

The Impact of Continuous Positive Airway Pressure Therapy on the Recurrence of Atrial Fibrillation in Patients with Obstructive Sleep Apnea after pulmonary vein isolation

Chinese Guidelines for the Diagnosis and Management of Atrial Fibrillation

Chinese guidelines for the diagnosis and management of atrial fibrillation

Contact Info

Product

Resources

About