Breathing pattern and lung volumes during exercise

Lind, Folke; Hesser, C. M.

doi:10.1111/j.1748-1716.1984.tb07381.x

Cited by 53 publications

(23 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the study of Bechbache et al (1979), a similar result has been observed for subjects who entrained their f to pedal rate. No such decreases in TI and TE have been found in the study of Lind & Hesser (1984). These aspects led us to suspect that our subjects might have displayed an entrainment off to pedal rate.…”

Section: Discussionmentioning

confidence: 67%

Effects of pedal rate on respiratory responses to incremental bicycle work.

Takano

1988

The Journal of Physiology

View full text Add to dashboard Cite

SUMMARY1. The influence of pedal rate on ventilatory response and breathing pattern during cycle exercise was studied in twelve untrained female subjects performing 15 W/min incremental work on a bicycle at 30 and 60 r.p.m. Comparisons were made within the range of aerobic work rate to avoid additional influences of a developing lactic acidosis.2. At each pedal rate, CO2 excretion (VC702) increased progressively to a level of

show abstract

Section: Discussionmentioning

confidence: 67%

Effects of pedal rate on respiratory responses to incremental bicycle work.

Takano

1988

The Journal of Physiology

View full text Add to dashboard Cite

show abstract

“…Objective exercise effort was assessed by the peak respiratory exchange ratio (VCO 2 /VO 2 ). Ventilatory efficiency was assessed by the slope of V E to VCO 2 , and ventilatory drive was assessed by the ratio of V T to T I (8). All analyses of ventilation and gas exchange data were conducted offline in a blinded fashion.…”

Section: Methodsmentioning

confidence: 99%

Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction

Olson

Johnson

Borlaug

2016

JACC: Heart Failure

110

View full text Add to dashboard Cite

Background Patients with heart failure and preserved ejection fraction (HFpEF) display elevation in left heart pressures, but it is unclear how this affects pulmonary gas transfer or its determinants at rest and during exercise. Objectives Compare measures of gas exchange at rest and during exercise in subjects with HFpEF to age and gender-matched controls. Methods HFpEF patients (n=20) and controls (n=26) completed a recumbent cycle ergometry exercise test with simultaneous measurement of ventilation and gas exchange. Diffusion of the lungs for carbon monoxide (DLCO) and subcomponents, pulmonary capillary blood volume (VC) and alveolar-capillary membrane conductance (DM), were measured at rest, matched low-intensity (20W), and peak exercise. Stroke volume was measured by transthoracic echocardiography to calculate cardiac output. Results Compared to controls, HFpEF subjects displayed impaired diastolic function and reduced exercise capacity. HFpEF subjects demonstrated 24% lower DLCO at rest (11.0±2.3 vs 14.4±3.3 mL/mmHg/min, p<0.01), related to reductions in both DM (18.1±4.9 vs 23.1±9.1 mL/mmHg/min, p=0.04), and VC (45.9±15.2. vs 58.9±16.2 mL, p=0.01). DLCO was lower in HFpEF compared to controls in all stages of exercise, yet its determinants showed variable responses. With low-level exercise, HFpEF subjects demonstrated greater relative increases in VC, coupled with heightened ventilatory drive and more severe symptoms of dyspnea compared to controls. At 20W exercise, DM was markedly reduced in HFpEF compared to controls. From 20W to peak exercise, there was no further increase in VC in HFpEF subjects, which in tandem with reduced DM, led to 30% reduction in DLCO at peak exercise (17.3±4.2 vs 24.7±7.1 mL/mmHg/min, p<0.01). Conclusion Patients with HFpEF display altered pulmonary function and gas exchange at rest and especially during exercise which contributes to exercise intolerance. Novel therapies that improve gas diffusion may be effective to improve exercise tolerance in patients with HFpEF.

show abstract

“…1; Grimby, Saltin & Wilhelmsen, 1971;Lind & Hesser, 1984;Jones et al 1985;Leblanc, Summers, Inman, Jones, Campbell & Killian, 1988 Work rate 3 (177 W). Between 6 and 37+ 6-6 min, Vo increased from 2-35 to 2-84 1 min-'; VC02 increased from 2-28 to 2-61 1 min-'; RER fell from 0 97 to 0-92.…”

Section: Incremental Exercisementioning

confidence: 99%