Breastfeeding, Human Milk and COVID-19—What Does the Evidence Say?

Mitoulas, Leon R.; Schärer-Hernández, Nania G.; Liabat, Severine

doi:10.3389/fped.2020.613339

Cited by 12 publications

(14 citation statements)

References 49 publications

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“…Holder pasteurization (62.5 °C for 30 min) prevents SARS-CoV-2 transmission through human milk, with partial loss of endogenous lysozyme, lactoperoxidase, lactoferrin, and reduction of neutralization capacity of SARS-CoV-2-specific IgA, while high-pressure pasteurization preserves this function. 39 , 71 – 73 , 84 , 85 …”

Section: Potential Strategies In Prevention Of Perinatal and Neonatal Covid-19mentioning

confidence: 99%

Neonates and COVID-19: state of the art

et al. 2021

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The SARS-CoV-2 pandemic has had a significant impact worldwide, particularly in middle- and low-income countries. While this impact has been well-recognized in certain age groups, the effects, both direct and indirect, on the neonatal population remain largely unknown. There are placental changes associated, though the contributions to maternal and fetal illness have not been fully determined. The rate of premature delivery has increased and SARS-CoV-2 infection is proportionately higher in premature neonates, which appears to be related to premature delivery for maternal reasons rather than an increase in spontaneous preterm labor. There is much room for expansion, including long-term data on outcomes for affected babies. Though uncommon, there has been evidence of adverse events in neonates, including Multisystem Inflammatory Syndrome in Children, associated with COVID-19 (MIS-C). There are recommendations for reduction of viral transmission to neonates, though more research is required to determine the role of passive immunization of the fetus via maternal vaccination. There is now considerable evidence suggesting that the severe visitation restrictions implemented early in the pandemic have negatively impacted the care of the neonate and the experiences of both parents and healthcare professionals alike. Ongoing collaboration is required to determine the full impact, and guidelines for future management. Impact Comprehensive review of current available evidence related to impact of the COVID-19 pandemic on neonates, effects on their health, impact on their quality of care and indirect influences on their clinical course, including comparisons with other age groups. Reference to current evidence for maternal experience of infection and how it impacts the fetus and then neonate. Outline of the need for ongoing research, including specific areas in which there are significant gaps in knowledge.

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Section: Potential Strategies In Prevention Of Perinatal and Neonatal Covid-19mentioning

confidence: 99%

Neonates and COVID-19: state of the art

et al. 2021

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“…The virus reaches almost all human organs, including the central and peripheral nervous systems Uversky et al, 2020a), and has unexpected vertical and horizontal infectivity potential (Elrashdy et al, 2020; LF action against SARS-CoV-2, on comparison of the human and animal LFs, and on determining whether the milk whey action against SARS-CoV-2 depends on LF alone or on other milk ingredients, such as human milk oligosaccharides (HMOs) and/or short-chain fatty acids. Our report fills these gaps and produces an overview of the field, providing answers to some fundamental questions, such as why breastfed children are mostly unaffected by COVID-19 (Fan et al, 2020;Liu et al, 2021;Mitoulas, Schärer-Hernández & Liabat, 2020). In addition, we enumerate the effects and the scenarios (based on viral and host factors) of how LF would work against SARS-CoV-2.…”

Section: Introductionmentioning

confidence: 99%

Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?

Mattar

Elrashdy

Almehdar

et al. 2021

PeerJ

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The world population is still facing the second wave of the COVID-19 pandemic. Such a challenge requires complicated tools to control, namely vaccines, effective cures, and complementary agents. Here we present one candidate for the role of an effective cure and/or complementary agent: lactoferrin. It is the cross-talking mediator between many organs/cellular systems in the body. It serves as a physiological, immunological, and anti-microbial barrier, and acts as a regulator molecule. Furthermore, lactoferrin has receptors on most tissues cells, and is a rich source for bioactive peptides, particularly in the digestive system. In the past months, in vitro and in vivo evidence has accumulated regarding lactoferrin’s ability to control SARS-CoV-2 infectivity in different indicated scenarios. Also, lactoferrin or whey milk (of human or other mammal’s origin) is a cheap, easily available, and safe agent, the use of which can produce promising results. Pharmaceutical and/or food supplementary formulas of lactoferrin could be particularly effective in controlling the gastrointestinal COVID-19-associated symptoms and could limit the fecal-oral viral infection transmission, through mechanisms that mimic that of norovirus infection control by lactoferrin via induction of intestinal innate immunity. This natural avenue may be effective not only in symptomatic patients, but could also be more helpful in asymptomatic patients as a main or adjuvant treatment.

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“…Difiriendo con un estudio realizado en Chile donde se comprobó en el 2014, la práctica de la lactancia materna en un 44,5% y que su meta deseada para el 2020 es llegar a un 60% (10). Otra investigación, sobre lactancia materna en el siglo XXI, expresó la práctica de amamantamiento exclusivo en un 37%, en lactantes menores de seis meses de edad, en los países de ingresos bajos y medianos, y esta cifra es aún menor en los países de ingresos altos (11)(12)(13). Existen estudios donde solo el 28.3% de los niños menores de 6 meses recibió lactancia materna exclusiva, 42.9% de los niños menores de 12 meses consumió fórmula infantil y 29% continuó lactando hasta los dos años (14,15).…”

Section: Discussionunclassified

Conocimientos De Las Gestantes Sobre Los Cuidados Domiciliarios Del Recién Nacido

Rochina¹,

Fernández²,

Ponce³

2021

Enferm. investig.

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Introducción: La mayoría de los padres de los neonatos requieren orientación del personal de salud, para los cuidados básicos domiciliarios de recién nacido. Objetivo: Determinar los conocimientos de las gestantes sobre los cuidados domiciliarios del recién nacido, controladas en el Centro de Salud Tipo C de Quero. Método: Estudio transversal, descriptivo, cuantitativo. El cual, por medio de un muestreo aleatorio simple de 72 gestantes, se aplicó cuestionario validado por expertos, sobre conocimientos de cuidados domiciliarios del recién nacido, basado en el Manual de Atención Integral a la Niñez 2018, del Ministerio de salud Pública del Ecuador, previa aplicación de una prueba piloto en 30 gestantes que no estuvo incluida en la muestra. La información obtenida, se analizó por el programa estadístico SPSS versión 24.0, para demostrar la consistencia de los resultados obtenidos por medio de frecuencia y porcentajes. Resultados: predominan las gestantes de 21 a 30 años 44,4%, poseen instrucción secundaria 61,1%, dependiente económicamente 47,2%, casadas 55,6%. Conocen sobre lactancia materna 97,2%, sobre higienización del recién nacido 44,4%, el cuidado y tiempo desprendimiento del cordón umbilical 48,6%. Desconocen la forma correcta de dormir 25% respectivamente. Conclusiones: Las gestantes están preparadas para asumir la responsabilidad de cuidar al recién nacido. Consideran la lactancia materna exclusiva, a libre demanda. Con conocimientos del baño, cuidado y tiempo del desprendimiento del cordón umbilical, signos de alarma para acudir inmediato al centro de salud. Existe un desconocimiento de la forma correcta de dormir, solo una minoría conocen que deben dormir de cubito supino (boca arriba) Palabras clave: atención del neonato, posición de dormir, lactancia materna, cuidados del cordón umbilical ABSTRACT Introduction: Most parents of newborns require guidance from healthcare professionals for basic home care of the newborn. Objective: To determine the knowledge pregnant women have about home care of newborns, at Type C Health Center of Quero. Method: Cross-sectional, descriptive, quantitative study. Through a simple random sample of 72 pregnant women, a questionnaire validated by experts was applied. It tested the knowledge of home care for newborns and it was based on the Manual of Comprehensive Care for Children 2018, of the Ministry of Public Health of Ecuador. A prior application of a pilot test in 30 pregnant women was not included in the sample. The information obtained was analyzed by the statistical program SPSS version 24.0, which showed the consistency of the results obtained by means of frequency and percentages. Results: prevalece of pregnant women aged 21 to 30 years (44.4%), with secondary education (61,1%), economically dependent (42,7%) and married (55,6%). Pregnant women who know about breastfeeding (97,2%) about newborn hygiene (44,4%), care and time of the umbilical cord detachment (48.6%). Patients who do not know the approppriate body position for sleep (25%). Conclusions: Pregnant women are prepared to be responsible for taking care of the newborn. They consider exclusive breastfeeding and on demand as necessary. They have knowledge on newborn bathing, care and time of the umbilical cord detachment, warning signs for immediate attention in a health center. There is a lack of knowledge of the correct way to sleep, only a minority know that they should sleep on the supine ulna (face up) Keywords: newborn care, sleeping position, breastfeeding, umbilical cord

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Breastfeeding, Human Milk and COVID-19—What Does the Evidence Say?

Cited by 12 publications

References 49 publications

Neonates and COVID-19: state of the art

Neonates and COVID-19: state of the art

Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?

Conocimientos De Las Gestantes Sobre Los Cuidados Domiciliarios Del Recién Nacido

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