Breast tuberculosis mimicking a malignancy: A rare case report with review of literature

Khandelwal, Rohan; Jain, Ila

doi:10.3233/bd-130350

Cited by 11 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Modified radical mastectomy is rarely indicated for patients with coexistent malignancy. 4,6,12 Our patient was started on Anti tubercular treatment with better response at 4 months of follow up.…”

Section: Discussionmentioning

confidence: 91%

“…6,8,9 Our patient had breast lump with discharging sinus at biopsy site and an evident axillary lymph node only during the follow up, which aided in the diagnosis of Tuberculosis.Radiological studies like mammogram and USG may mislead in diagnosis and differentiating tuberculosis of breast, granulomatous fat necrosis and carcinoma of breast, as seen in our case, where in USG was suggestive of carcinoma of breast. Rather USG would aid in locating suspicious area for guiding FNAC.…”

mentioning

confidence: 74%

“…Like skeletal muscles and spleen, breast tissue provides an unfavorable environment for the tubercle bacilli, which explains the lower incidence of Tuberculosis in the breast. 6 Secondary tuberculosis of breast is more common than primary and few theories have been postulated for understanding the mode of spread. Among which, most commonly spread occurs via lymphatics by retrograde extension from the axillary node, followed by contiguous spread from ribs, pleural space or rectus sheath from an intra-abdominal source or by hematogenous spread.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Granulomatous fat necrosis of breast a diagnostic dilemma: a rare case report

Mukesh

Rajan

2022

Int Surg J

View full text Add to dashboard Cite

Fat necrosis in breast is a rare benign condition, which can mimic carcinoma and Tuberculosis (TB) of breast in both clinical and radiological assessment. Histopathology in such cases may distinguish granulomatous lesion from carcinoma, however granulomas are identified in both fat necrosis and tuberculosis which is difficult to differentiate. Fat necrosis in breast is often not associated with axillary lymph nodes, which can differentiate fat necrosis from tuberculosis and breast carcinoma. But high index of suspicion is always required. We hereby report a case of a 40-year old female, who presented with lump in the right breast which lead to diagnostic dilemma.

show abstract

Section: Discussionmentioning

confidence: 91%

mentioning

confidence: 74%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Granulomatous fat necrosis of breast a diagnostic dilemma: a rare case report

Mukesh

Rajan

2022

Int Surg J

View full text Add to dashboard Cite

show abstract

“…The breast tuberculosis can be confused with breast carcinoma, specially in elder women [27,28,69,124], who present an isolated ill defined, irregular, occasionally hard breast lump without sinuses/fistula, but pain is present more frequently in the tuberculous lump than in carcinoma. Involvement of the nipple and areola is rare in tuberculosis, but fixation of the lump to the skin may be present as a part of the inflammatory process, which is present in both pathological entities A high index of suspicion needs to be maintained if a breast lump is associated with a sinus or indolent lump in an immigrant women if this is encountered in the western countries.…”

Section: Differential Diagnosis 61 Differentials For Breast Tubercumentioning

confidence: 99%

Breast and Cervix Uteri: Rare Locations for Mycobacterium Tuberculosis Infections and Complications-Cases Report and Literature Review

Russu¹,

Nastasia²,

Degeratu³

et al. 2018

Tuberculosis

View full text Add to dashboard Cite

Breast and cervix uteri are rare locations for Mycobacterium tuberculosis (MbT) infection and MbT association to cervical cancer is more rare in European countries. This chapter analyses two cases of rare locations of tuberculosis (TB) in young Romanian women. The first patient presented a chronic primary TB breast abscess, non-pregnancy related with periods of apparent healing and repeated areolar fistula formation. In the second case, the unexpected discovery of secondary TB endocervical granulomatous inflammation with caseous necrosis on a radical hysterectomy specimen, performed after chemoradiotherapy for squamous nonkeratinizing cell carcinoma is presented. Worldwide incidence, risk factors, hypothetic mechanisms of primary/secondary breast and cervix uteri MbT infection, the association to highrisk HPV, microbiological diagnosis difficulties, the differentials to pyogenic abscesses, other chronic granulomas and breast cancer treatment issues are presented in the reviewed literature, focusing on the peculiarities of these rare locations and complications. It is recalled an old concept of "therapeutic antitubercular" test when all other assessments steps are usefulness.

show abstract

“…Bilateral involvement has been documented in 3–30% of all cases 1 . The typical presentation involves a lump in the central or upper outer quadrant, influenced by axillary lymph nodes 8 , 23 . Our case exhibited extensive unilateral upper outer quadrant involvement without associated lymphadenopathy.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic challenge: a case report of primary breast tuberculosis mimicking recurrent pyogenic breast abscess

Thapaliya,

Kumari,

Oli

et al. 2024

Annals of Medicine &Amp; Surgery

View full text Add to dashboard Cite

Introduction: Breast tuberculosis is a rare form of extra pulmonary tuberculosis with its primary form considered even rarer. Case presentation: A 28-year-old female initially diagnosed with a breast abscess presented with chronic right breast pain and nipple discharge. Despite initial treatment, symptoms recurred, and further investigations revealed a space-occupying lesion. Fine needle aspiration confirmed recurrent breast abscess, but subsequent DNA detection of tubercular bacilli in the pus sample led to a diagnosis of primary breast tuberculosis, necessitating anti-tubercular therapy. Clinical discussion: Breast tuberculosis, being rare and often misdiagnosed as an abscess, poses diagnostic challenges. However, Persistent symptoms despite treatment should prompt consideration of breast tuberculosis in TB endemic regions. Conclusion: Primary Breast Tuberculosis might not have any systemic symptoms to drag the clinician towards a possible diagnosis so culturing the aspirate for acid-fast bacilli or looking for MTB DNA in the available clinical sample should always be kept in mind for better outcomes.

show abstract

Breast tuberculosis mimicking a malignancy: A rare case report with review of literature

Cited by 11 publications

References 7 publications

Granulomatous fat necrosis of breast a diagnostic dilemma: a rare case report

Granulomatous fat necrosis of breast a diagnostic dilemma: a rare case report

Breast and Cervix Uteri: Rare Locations for Mycobacterium Tuberculosis Infections and Complications-Cases Report and Literature Review

Diagnostic challenge: a case report of primary breast tuberculosis mimicking recurrent pyogenic breast abscess

Contact Info

Product

Resources

About