Breast Reconstruction with Myocutaneous Flaps in Previously Irradiated Patients

Histomorphologische Strukturveränderungen von Kopf-Hals-Gefäßen nach prä- oder postoperativer Radiotherapie

“…Uneinheitlich sind in der Literatur die Angaben zur klinischen Komplikationsrate von freien vaskulären Transplantaten bei vorbestrahlten Patienten. Die Komplikationsraten reichen von 0% bis 39% [1,2,5,15,16,40].…”

Achieving autologous breast reconstruction for breast cancer patients in the setting of post-mastectomy radiotherapy

“…As a result, there is scarce data examining the effect of radiotherapy on these forms of reconstruction. Although residual radiated tissue can predispose to infection and extrusion of the flap, past history of irradiation does not confer an increased risk of flap loss [47]. Similarly, Apffelstaedt showed no significant difference in complication rates between preoperative radiation and non-irradiated patients [54].…”

“…Pedicled TRAMs, when undertaken in irradiated tissue beds, have complication rates reported to be in the order of 25-33% [22,47]. Following radiotherapy, pedicled TRAMs have been shown to have a higher incidence of skin and fat necrosis [37], flap failure [48] and major infection [28].…”

Alloplastische Brustrekonstruktion nach Mastektomie

“…sekundärer Expander-Implantat-Rekonstruktion bei Beachtung der Indikationsstellung geringer als nach autologen Sekundärre-konstruktionen [8,17]. Sofortkomplikationen umfassen Hämatome, Hautnekrosen, Infektionen und Schmerzen.…”