Breast masses in childhood and adolescence

Boothroyd, A. E.; Carty, Helen

doi:10.1007/bf02020157

Cited by 62 publications

(15 citation statements)

References 22 publications

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“…Other primary tumors include: lymphoma; leukaemia; rhabdomyosarcoma; and neuroblastoma [1]. The autopsy incidence of metastases to the breast from malignant neoplasms other than primary breast carcinoma varies from 1.7 to 6.6 %; however, the clinically observed rate of metastases ranges from 0.5 to 1.3 % [3].…”

Section: Discussionmentioning

confidence: 99%

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Metastastic rhabdomyosarcoma to the breast

et al. 2001

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Rhabdomyosarcoma is a common extramammary primary malignancy in childhood that rarely metastasises to the breast. We present a patient with primary sinonasal rhabdomyosarcoma who was in remission when she developed breast metastases. We describe particular imaging findings of this disease, using ultrasound and MR imaging. To our knowledge, MR findings have only been described in one previous case report in the literature.

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Section: Discussionmentioning

confidence: 99%

“…

IntroductionAlthough rhabdomyosarcoma is a common aggressive primary malignancy in the pediatric age group, metastatic deposits to the breast rarely occur and are mainly seen in adolescent girls [1,2,3]. The primary tumor is usually of the alveolar histological type and located in the extremities [4,5,6].

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confidence: 99%

Metastastic rhabdomyosarcoma to the breast

et al. 2001

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“…Breast involvement is very rare, both as a primary or as a metastatic site [7]. Only a few cases of primary RMS of the breast in children have been reported in the literature (table 1) [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22]. Due to the extremely rare incidence of primary breast RMS, radiologic imaging features have yet to be clearly defined.…”

Section: Introductionmentioning

confidence: 99%

Primary Rhabdomyosarcoma of the Breast: Imaging Findings and Literature Review

et al. 2018

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Background: Primary breast rhabdomyosarcoma (RMS) can occur in children. There is a lack of knowledge regarding radiologic findings and added diffusion-weighted magnetic resonance imaging (MRI) features of RMS in the literature. Case Report: A 12-year-old girl was diagnosed with primary alveolar RMS of the breast. Gray scale ultrasound revealed posterior acoustic enhancement behind a well-circumscribed, multilobulated hypoechoic mass. Doppler ultrasound revealed increased peripheral and central vascularity. Hypointense septations on T2-weighted image exhibiting more enhancement than the stroma on late gadolinium-enhanced images were striking within a hyperintense mass. A hyperintense hemorrhagic focus on T1-weighted image was present in the absence of any necrosis. Avid enhancement on early postcontrast images proceeding from the periphery to the center was depicted. Conclusion: A rapidly enlarging mass with an echogenic peripheral rim together with posterior acoustic enhancement on gray scale ultrasound, intense vascularity on Doppler ultrasound, axillary lymphadenopathy, and satellite nodules on MRI should raise suspicion. Enhancing central and peripheral septations are suggestive of RMS. Dynamic contrast-enhanced MRI in suspected cases can provide valuable data in the differential diagnosis.

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“…Ultrasound may be more suited to imaging-suspected breast pathology in young patients than mammograms because it better detects masses in fibroglandular breasts than in fatty breasts (9,14,15). Aspiration cytology demonstrates sheets of hyperplastic, benign, ductal epithelial cells with myoepithelial cells and a background of benign bipolar nuclei and blood, without inflammatory fat cells (12).…”

Section: Juvenile Fibroadenomamentioning

confidence: 99%