Breast implant–related fibromatosis: a rare but important adverse effect

Breast-Implant-Related Fibromatosis in a Patient with Free Silicone Injection: a Case Report

“…2,4,6,7 To date, fewer than 50 cases of implant-related breast fibromatosis have been reported. [2][3][4][6][7][8][9][10][11][12][13] Reported cases are seen more often with silicone implants than saline implants, possibly due to the higher prevalence of the former. 6 Fibromatoses are usually reported to develop within 2 to 3 years of implant surgery.…”

“…Calcifications are rare. [4][5][6]12,14 On ultrasound, features likewise vary, ranging from a circumscribed parallel mass to a non-parallel hypoechoic mass with obscured, irregular or spiculated borders. More common features include hypoechogenicity, irregular border and posterior acoustic shadowing.…”

“…The treatment of breast fibromatoses is evolving and remains controversial, but there had been discussion of surgery (most commonly described is wide local excision with clear margins), and systemic therapy with nonsteroidal anti-inflammatory drugs such as sulindac, hormone therapy with tamoxifen, and tyrosine kinase inhibitors have been used. [4][5][6][7][8]10,12,14 Radiotherapy is suggested to also play a role in management. [5][6][7][8]12 It should be kept in mind that local recurrence is not uncommon despite treatment, and follow-up is required.…”

“…[4][5][6][7][8]10,12,14 Radiotherapy is suggested to also play a role in management. [5][6][7][8]12 It should be kept in mind that local recurrence is not uncommon despite treatment, and follow-up is required. 4,5 In view of the complexity of diagnosis and management, these cases should be presented at multidisciplinary meetings to reach a conjoint decision.…”