Breast Implant-associated Anaplastic Large Cell Lymphoma after Breast Reconstruction for Breast Cancer

Abstract

A patient initially operated on for aesthetic breast augmentation had a round-textured silicone gel prosthesis, Poly Implants Prothèse , placed in a subglandular plane. The patient developed a bilateral capsular contracture, and 4 years later, underwent a complete bilateral capsulectomy with an exchange of Mentor 215 cm 3 textured cohesive silicone-gel ultra-high profile breast implants in the same subglandular plane. One year later, the patient developed cancer in the right breast, so it was decided to perform a bilateral mastectomy and reconstruction with 265 cm 3 (left) and 310 cm 3 (right) Natrelle (Allergan) round-textured silicone-gel implants in a submuscular plane. Seven years after the last surgery, the patient developed a seroma in the left breast (breast opposite to the one that developed the cancer), and seroma studies reported a CD30-positive anaplastic large cell lymphoma associated with the breast prosthesis. Therefore, bilateral capsulectomy and explantation of both implants with breast reconstruction with autologous tissue were performed.

Artistry and Aesthetics in Breast Reconstruction: Raising the Bar

“…Implant-based breast reconstruction (IBR) has also experienced important advancements, despite becoming less popular after the association between anaplastic large cell lymphoma (ALCL) and macro-textured implants [ 6 ]. Round implants have become more popular for breast reconstruction; however, these devices may have issues around implant displacement and lower pole tissue stretch.…”