Breast Imaging and Intervention in the Overweight and Obese Patient

Destounis, Stamatia; Newell, Mary S.; Pinsky, Renee W.

doi:10.2214/ajr.10.5556

Cited by 29 publications

(28 citation statements)

References 18 publications

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“…One of the most common reasons women give is the embarrassment of being weighed or having to undergo a physical exam with even more embarrassing aspects to endure (e.g. too small gowns, examination tables, instruments) [28,29,31]. A further crucial point is the physician's attitude towards obese patients.…”

Section: Discussionmentioning

confidence: 99%

Impact of Body Mass Index on Prognostically Relevant Breast Cancer Tumor Characteristics

Eichholzer

Huang²,

Modlasiak³

et al. 2013

Breast Care

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Background: This study analyzes the association of body mass index (BMI) and prognostically relevant breast cancer (BC) characteristics in a country that has been rather spared of the global obesity epidemic. Patients and Methods: Based on 20-year data (1999-2009, n = 1,414) of the prospective relational BC database of the University Hospital Basel, Switzerland, the associations between BMI, tumor size and stage, histological subtype, grading, hormonal receptor status, HER2 status and ‘triple-negative' status were evaluated. Multivariate analysis considered BMI and patient's age. Results: The association between increasing BMI and the above-mentioned variables were as follows (results described in each case: Beta-coefficient or odds ratio, 95% confidence interval, p value): tumor size, (1) entire cohort: 0.03 (0.01-0.05), p < 0.001, (2) tumor found by self-palpation: 0.05 (0.03-0.07), p < 0.001, (3) tumor found by radiological examination: 0.03 (0-0.07), p = 0.044; advanced TNM stage: 1.16 (1.02-1.31), p = 0.022; histological subtype: 1.04 (0.89-1.22), p = 0.602; unfavorable grading: 1.11 (1.00-1.25), p = 0.057; positive estrogen receptor status: 0.95 (0.83-1.09), p = 0.459; positive HER2 status: 0.92 (0.74-1.15), p = 0.467; presence of a ‘triple-negative' carcinoma: 1.19 (0.93-1.52), p = 0.165. Consideration of only postmenopausal BC patients (n = 1,063) did attenuate the results, but did not change the direction of the associations with BMI. Conclusion: BMI was positively associated with TNM stage, grading and tumor size for tumors that were found by self-detection, as well as for those lesions detected by radiological breast examinations.

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Section: Discussionmentioning

confidence: 99%

Impact of Body Mass Index on Prognostically Relevant Breast Cancer Tumor Characteristics

Eichholzer

Huang²,

Modlasiak³

et al. 2013

Breast Care

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“…The research challenges in ultrasound imaging is generation of 3-D images to accurately differentiate benign and malignant tumors and ultrafast ultrasound imaging (4D imaging) for moving organs like heart and liver [79][80][81][82]. Lastly use of ultrasound images in surgery and planning of cancer and molecular targeting is newest development in Ultrasound research [83,84]. Image Fusion can be performed on images acquired from different sources, at different times, with different resolutions and with different focus [86][87][88][89][90].…”

Section: Ultrasound (Us)mentioning

confidence: 99%

Advances in Biomedical Imaging and Image Fusion

Chandrashekar¹,

Sreedevi²

2018

IJCA

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Biomedical imaging is a series of procedures which create images of the human body, or parts of the body, to help screen for possible illness or injury, diagnose the likely cause of symptoms and monitor health conditions or the effects of treatment. The objective of the paper is to provide an overview about various bio medical imaging techniques used in detection and diagnosis of Cancer. Each of these imaging techniques provides information about the anatomy, chemical or physiologic phenomena of the human body which are studied independently by doctors to identify Cancer. The biomedical imaging systems, applications, benefits, drawbacks and research challenges are discussed. Image Fusion and its role in Bio medical imaging is also discussed. Image Fusion is the process of fusing two or more bio medical images which contain complementary information into a single composite image. These enrich image quality and avoid redundancy thereby increase the clinical applicability of medical images for cancer detection, prognosis and treatment planning of Cancer.

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“…According to this review, many physicians held a negative attitude toward obese patients, including beliefs that they were lazy, undisciplined, awkward and weak-willed [72]. These attitudes may play a role in hindering the recommendation of screening patients for cancer and may make obese individuals feel as though they are being judged, leading them to avoid interaction with physicians [73]. In the same study by Puhl and Brownell, patients' perceptions of how they are treated owing to their size were also investigated.…”

Section: Barriers To Gynecologic and Bc Screening Among Obese Individualsmentioning

confidence: 99%

“…In addition to attitudes and beliefs of physicians concerning obese patients, discomfort and equipmentrelated issues, there are structural issues that present a barrier to adequate screening once the decision to screen has been made. For example, larger breast size can decrease the efficacy of a CBE or self-exam, making it difficult to detect changes in breast tissue that can go unnoticed for long periods of time, leading to an increased risk for a higher stage of disease upon diagnosis [73]. There is some literature demonstrating that obese women who are embarrassed about their weight are reluctant to get screening.…”

Section: Barriers To Gynecologic and Bc Screening Among Obese Individualsmentioning

confidence: 99%

Advancements in the Use of Blood Tests for Cancer Screening in Women at High Risk for Endometrial and Breast Cancer

Ambeba

Linkov

2011

Future Oncol.

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Several years ago, it was argued that the identification of serum biomarkers is one of the most promising approaches for the detection of early-stage malignant or even premalignant lesions. In this review, the need to establish better monitoring protocols is described for obese women who are at higher risk for the development of malignancies commonly associated with excess weight; specifically endometrial and postmenopausal breast cancer. These cancers have been chosen for this review article as our aim was to focus on female cancers that have been linked with obesity. Cancer screening is essential in detecting disease in its earliest stage in order to reduce morbidity and mortality; however, effective screening is not available for many cancer types. Even for cancers that have effective screening protocols available, there are barriers to screening in obese individuals, such as reduced mobility and embarrassment. These barriers often delay screening in these vulnerable population groups, leading to detection of the disease at a more advanced stage and ultimately leading to a poorer prognosis. As of today, biomarkers do not replace but augment imaging and other existing screening approaches. Future development of blood- or urine-based biomarkers as a way to screen individuals at high risk for certain cancers may prove to be an excellent method for overcoming the barriers that individuals at high risk are facing today. The overall purpose of this manuscript is to provide an overview of screening techniques and to identified barriers and alternate biomarker-based approaches for improvement of endometrial and breast cancer screening in obese women.

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Breast Imaging and Intervention in the Overweight and Obese Patient

Abstract: This article discusses social factors and physical limitations that influence these patients' desires and ability to seek health care, specifically breast care and the problems that arise during imaging and interventional procedures.

Cited by 29 publications

References 18 publications

Impact of Body Mass Index on Prognostically Relevant Breast Cancer Tumor Characteristics

Impact of Body Mass Index on Prognostically Relevant Breast Cancer Tumor Characteristics

Advances in Biomedical Imaging and Image Fusion

Advancements in the Use of Blood Tests for Cancer Screening in Women at High Risk for Endometrial and Breast Cancer

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