Breast-feeding after breast cancer: if you wish, madam

Azim, Hatem A.; Bellettini, Giulia; Gelber, Shari; Peccatori, Fedro Alessandro

doi:10.1007/s10549-008-9983-7

Cited by 42 publications

(34 citation statements)

References 49 publications

(44 reference statements)

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“…Italian oncologists agreed on the importance of breastfeeding in BCa patients who underwent surgery, and on the need to counsel patients about it. Advantages of breastfeeding on babies' health are undisputed but many studies have shown also the positive role of breastfeeding on BCa patients outcome [29,30]. After surgery and radiotherapy the treated breast is usually hypotrophic, produces less or no milk and therefore, it is not possible to breastfeed from it.…”

Section: Discussionmentioning

confidence: 99%

Attitudes on fertility issues in breast cancer patients: an Italian survey

Biglia

Torrisi

D’Alonzo

et al. 2015

Gynecological Endocrinology

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Background: Fertility issues should be discussed with young women before the start of any anticancer treatment. The study is aimed to investigate the attitude on fertility among Italian oncologists and breast surgeons dealing with BCa, and to report the consensus achieved on specific statements. Methods: One hundred and sixty-two panelists anonymously expressed an opinion through a web-based platform on 19 statements based on the Delphi method. Results: Ninety-one percent of oncologists considered important to discuss with patients about fertility issues and 83% believed estrogens could stimulate the growth of hidden cancer cells in ER + tumors. Difficulties in accessing fertility preservation procedures were mainly due to patients' reluctance, but also to lack of coordination with the assisted reproduction specialists. No full consensus was reached on the prognostic role of pregnancy after BCa. Fifty-four percent of oncologists declared that pregnancy does not affect oncologic prognosis. Treatment with GnRHa during chemotherapy was considered the only mean for preserving ovarian function. Conclusions: Fertility preservation in BCa patients is a well-accepted practice among Italian oncologists. A poor knowledge of this specific issue emerged from the survey, even if a certain degree of agreement was observed on most fertility-related issues.

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Section: Discussionmentioning

confidence: 99%

Attitudes on fertility issues in breast cancer patients: an Italian survey

Biglia

Torrisi

D’Alonzo

et al. 2015

Gynecological Endocrinology

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“…Women previously treated for BC face a unique physical and emotional status that might impact their decisions and ability to breastfeed [53]. In a single analysis comparing 25 and 27 BC survivors who had bottle-fed and breastfed their children, respectively, 6 and 1 deaths were reported for the 2 groups [54]. While no formal statistics were conducted due to the limited sample, the results appear reassuring.…”

Section: Is Breastfeeding After Breast Cancer Feasible and Safe?mentioning

confidence: 98%

“…To the best of our knowledge, no other prospective or retrospective study has specifically addressed this question. From a feasibility perspective, successful breastfeeding following BC from the ipsilateral breast is in the range of 30% [54] and may be restricted by surgical approaches (i.e. proximity of the incision to the areola/nipple), or the dose and type of radiotherapy [55][56][57].…”

Section: Is Breastfeeding After Breast Cancer Feasible and Safe?mentioning

confidence: 99%

Pregnancy after Breast Cancer: Myths and Facts

Pagani

Azim²

2012

Breast Care

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Most young breast cancer survivors consider reproductive issues to be of great importance, but many questions remain undervalued and unanswered. Overall, available data support the safety and feasibility of pregnancy and breastfeeding after breast cancer. The accuracy of the evidence is however limited by: i) the retrospective and frequently incomplete population-based nature of the data, ii) data not representing the entire population, iii) patient-related effects, iv) underpowered sample size, and v) lack of control for biological factors and risk determinants. We review the available evidence in light of these limitations which outline the need for prospective data collection and focused priority research.

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“…De qualquer forma, o aleitamento na mama irradiada não é recomendado devido ao risco da mulher desenvolver mastite, que, caso ocorra, será de manejo delicado. 27,28 A maioria das drogas (principalmente, os agentes alquilantes) é excretada no leite humano. De forma geral, a lactação deve ser evitada durante a quimioterapia, uso de transtuzumab, lapatinib e terapia endócrina.…”

Section: Lactaçãounclassified

Câncer de mama na gravidez: Diagnóstico e Tratamento

Monteiro

Menezes

Nunes

et al. 2014

Revista Hospital Universitário Pedro Ernesto

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ResumoO objetivo do estudo é avaliar o diagnóstico e a terapêutica do câncer de mama em gestantes, visto que a gravidez pode potencialmente gerar retardo na abordagem da doença e, consequentemente, pior prognóstico do que na mulher não gestante. Associa-se ainda o baixo índice de suspeição da doença neste período e relutância de médicos e pacientes em realizar testes radiográficos e procedimentos invasivos. O câncer de mama é a neoplasia maligna feminina mais frequente. Sua incidência na gestação é baixa, variando de 1:3000 a 1:10.000 gravidezes, apresentando-se geralmente em estágio avançado durante a gravidez. A condução do caso frequentemente gera dificuldades e angústia para a gestante, sua família e para os profissionais de saúde envolvidos, em função do dilema criado entre a terapia ideal para a mãe e o bem-estar do feto. O diagnóstico baseia-se no teste triplo que consiste em exame clínico, imagem e biópsia, visando avaliar a extensão da doença na mama e nos linfonodos, identificar múltiplos focos ou eventual tumor bilateral, bem como prevenir metástases sistêmicas e controlar localmente a doença. O adiamento da terapêutica, a fim de proteger o concepto, pode comprometer a saúde materna. A mastectomia radical modificada e a radical clássica podem ser utilizadas com segurança. Deve-se realizar o esvaziamento axilar, pois metástases são comumente encontradas na gravidez e o comprometimento linfonodal influencia na escolha da quimioterapia. Evidências sugerem segurança e eficácia do esquema 5-fluorouracil, doxorrubicina (ou epirrubicina) e ciclofosfamida durante o segundo e o terceiro trimestres da gestação. A radioterapia deve ser adiada, sempre que possível, para depois do parto. Este estudo visa ainda incentivar o exame das mamas durante o exame ginecológico de rotina e pré-natal, conscientizando paciente e equipe de saúde de sua importância no ciclo grávido-puerperal. Descritores:Câncer de mama; Gravidez; Diagnóstico; Tratamento. AbstractThe aim of the study is to evaluate diagnosis and treatment of breast cancer in pregnant women, since pregnancy can potentially generate delay in disease approach and consequently worst prognosis than in non-pregnant women. There is also a low index of suspicion of the disease in this period and reluctance of patients and physicians to perform radiographic tests and invasive procedures. Breast cancer is the most common female malignancy. Its incidence in pregnancy is low, ranging from 1:3000 to 1:10,000 pregnancies, usually presenting at an advanced stage during pregnancy. The disease management often generates difficulties and distress for the mother, her family and health professionals involved, depending on the dilemma created between the ideal therapy for the mother and fetus welfare. Diagnostic approach is based on triple test consisting of clinical, imaging and biopsy examination to evaluate disease extension in breast and lymph nodes, identify possible multiple foci or bilateral tumors, and prevent systemic metastasis and manage local disease. Therapy delay in ord...

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Breast-feeding after breast cancer: if you wish, madam

Cited by 42 publications

References 49 publications

Attitudes on fertility issues in breast cancer patients: an Italian survey

Attitudes on fertility issues in breast cancer patients: an Italian survey

Pregnancy after Breast Cancer: Myths and Facts

Câncer de mama na gravidez: Diagnóstico e Tratamento

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