Breast carcinoma metastatic to paranasal sinuses

Austin, John R.; Kershiznek, Matthew M.; McGill, D. A. F.; Austin, Sara G.

doi:10.1002/hed.2880170217

Cited by 25 publications

(20 citation statements)

References 14 publications

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“…Excluded from most epidemiological data are metastases to the nasal cavity and the paranasal sinuses, which, in our personal experience, account for a notable portion of malignant tumors 86 ORL 2004;66:85-97 Götte/Hörmann encountered at this anatomical site. Breast cancer, prostate cancer and renal cell carcinoma metastases are among the most frequent histological types, and single case reports are regularly published in otorhinolaryngological journals [10][11][12].…”

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confidence: 99%

Sinonasal Malignancy: What’s New?

Götte¹,

Hörmann²

2004

ORL

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Tumors of the nasal cavity are located at a complex anatomic site and show a huge histological diversity. Although dealing with a rare malignancy, the last decade has brought – besides new histological and clinical classifications – a variety of new insights into etiological agents, tumor biology and therapeutic concepts as well as valuable overviews of rare histological subtypes. This review tries to disentangle the different medical and scientific aspects of the most frequently encountered histological types of tumors in the nasal cavity and the paranasal sinuses. We concentrate on epidemiology, classification, etiology, cytogenetics and molecular genetics, outcome and prognosis as well as treatment modalities, as far as the past few years have brought considerable new insights. Our principal aim is to provide the clinician with important data from publications of the last decade.

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confidence: 99%

Sinonasal Malignancy: What’s New?

Götte¹,

Hörmann²

2004

ORL

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“…Breast cancer metastases to the sino-nasal-orbital area is an infrequent occurrence; with only five reported cases in the English literature [5,1,4,6,2]. This is an unprecedented case of orbital apex syndrome from metastatic breast cancer.…”

Section: Resultsmentioning

confidence: 86%

Orbital Apex Syndrome as the Initial Presentation of Metastatic Breast Cancer

Loftus¹,

Tan²

2013

Journal of Case Reports in Medicine

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Breast cancer metastases to the paranasal sinuses are an infrequent occurrence, and diagnosis is often delayed due to misdiagnosis of headache or sinusitis. We present a case of a 49-year-old female with a history of breast cancer status post bilateral mastectomy whose metastatic breast cancer to the paranasal sinuses first manifested as orbital apex syndrome. In the clinical picture of sinusitis with orbital complications, awareness for metastatic disease in patients with a history of cancer should be maintained in the appropriate clinical setting. Physicians should be mindful of the possibility of this diagnosis as these patients are often initially evaluated for non-specific symptoms such as headache and congestion. This is an unprecedented case of metastatic breast cancer first presenting as orbital apex syndrome.

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“…However, breast cancer can also give metastases to the paranasal sinuses. 1,[10][11][12] In the literature, only one case of metastatic melanoma to the ethmoid sinus has been reported. 13 In-patient with renal cancer and frequent epistaxis should be suspected and roll out metastasis from renal cancer to sinonasal area.…”

Section: Discussionmentioning

confidence: 99%

Metastatic paranasal sinuses adenocarcinoma from breast carcinoma, a rare event: a case report

Khurayzi

Al-Shahrani

2017

Int J Otorhinolaryngol Head Neck Surg

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<p>Metastases to the nose and paranasal sinuses usually respond poorly to treatment and have a poor prognosis. We present a 31 year old lady with rare metastatic paranasal sinuses lesion which is adenocarcinoma that metastasis from breast carcinoma. All of clinical presentation, radiological findings, histopathological and immunohistochemically markers examination reveal metastatic adenocarcinoma. This study presents rare metastasis in head and neck cancer especially from breast to paranasal sinuses.</p>

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Breast carcinoma metastatic to paranasal sinuses

Abstract: We conclude that breast carcinoma metastatic to the PNS is rare and has been uniformly fatal because, as disseminated disease, it does not respond well to conventional systemic therapies.

Cited by 25 publications

References 14 publications

Sinonasal Malignancy: What’s New?

Sinonasal Malignancy: What’s New?

Orbital Apex Syndrome as the Initial Presentation of Metastatic Breast Cancer

Metastatic paranasal sinuses adenocarcinoma from breast carcinoma, a rare event: a case report

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