Breast Cancer in Young Women After Treatment for Hodgkin’s Disease During Childhood or Adolescence

Abstract

Women who were treated for HD in childhood or adolescence have an increased risk of developing breast cancer as young adults. The risk is associated with prior radiotherapy and with the age at which it was administered (the pubertal phase). Because of these findings, a structured breast cancer screening project for this high-risk group has been initiated in collaboration with the German Consortium for Hereditary Breast and Ovarian Cancer (Deutsches Konsortium für familiären Brust- und Eierstockkrebs).

Breast Cancer as a late complication of treatment for lymphoma in children and adolescents

“…[5] Many patients who have had breast cancer later after Hodgkin's lymphoma treatment in childhood were treated with radiotherapy with radiation field in the thoracic region and during puberty. [1,2] The same study says that women found the new cancer, on aver-age, 35.1 years old, revealing a latency of 20.7 years. [1] a third malignancies may occur in some patients.…”

“…[1,2] The same study says that women found the new cancer, on aver-age, 35.1 years old, revealing a latency of 20.7 years. [1] a third malignancies may occur in some patients. [6] The risk of developing late breast cancer is higher 24 times than in the general population aged 25 to 45 years.…”

“…[1] The association between chemotherapy and radiotherapy for the treatment of Hodgkin's disease has harmful effects long term and should be rethought your indiscriminate use. [2] the breast cancer was observed in women patients at a medium range of 22 years after treatment for the first cancer in childhood and may vary from 14.3 to 32.1 years.…”

“…[2] the breast cancer was observed in women patients at a medium range of 22 years after treatment for the first cancer in childhood and may vary from 14.3 to 32.1 years. [1] Other malignant diseases can also occur later after this same situation, such as thyroid Cancer, Skin Cancer not melanoma, leukemia or non-Hodgkin's lymphoma; or non malignant problems as cardiotoxiciy. [1,2,3,4] As healing is achieved in many patients with the disease in childhood, the long-term effects and quality of life of survivors represent the biggest challenge in the post-treatment.…”

“…[1] Other malignant diseases can also occur later after this same situation, such as thyroid Cancer, Skin Cancer not melanoma, leukemia or non-Hodgkin's lymphoma; or non malignant problems as cardiotoxiciy. [1,2,3,4] As healing is achieved in many patients with the disease in childhood, the long-term effects and quality of life of survivors represent the biggest challenge in the post-treatment. [5] Many patients who have had breast cancer later after Hodgkin's lymphoma treatment in childhood were treated with radiotherapy with radiation field in the thoracic region and during puberty.…”