1999
DOI: 10.3892/or.6.5.1001
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Breast cancer in the contralateral breast: incidence and histopathology after unilateral radical treatment of the first breast cancer.

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Cited by 6 publications
(2 citation statements)
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“…In the remaining 8 cases, clinical criteria were conclusive in 4, whereas all 8 cases were classified successfully by partial allelotyping, with concordance with the assessment using clinical criteria. Similar findings were implied in a largescale study 20 in which 66% of the second breast carcinomas were shown to be of a differing histotype, indicating at least 66% of the tumors as distinct primary tumors. Our study provides evidence at the genomic level of the epidemiologic observation that the eventual outcome and prognosis for patients with bilateral mammary carcinomas were similar to those for unilateral disease, 21,22 implying a new primary tumor rather than a much later staged distant organ metastasis.…”
Section: Discussionsupporting
confidence: 85%
“…In the remaining 8 cases, clinical criteria were conclusive in 4, whereas all 8 cases were classified successfully by partial allelotyping, with concordance with the assessment using clinical criteria. Similar findings were implied in a largescale study 20 in which 66% of the second breast carcinomas were shown to be of a differing histotype, indicating at least 66% of the tumors as distinct primary tumors. Our study provides evidence at the genomic level of the epidemiologic observation that the eventual outcome and prognosis for patients with bilateral mammary carcinomas were similar to those for unilateral disease, 21,22 implying a new primary tumor rather than a much later staged distant organ metastasis.…”
Section: Discussionsupporting
confidence: 85%
“…When there is cancer in one breast, the potential risk that cancer will be found in the contralateral breast in the future is not great, but it still exists, and we cannot ignore it. The likelihood that breast cancer will appear in the contralateral side is 6% after 10 years and 9% after 20 years 13 14 15 16 . Therefore, a surgeon should explain this possibility to patients and evaluate the opposite breast for cancer development properly by regular physical examinations, mammography, and magnetic resonance imaging before surgery 17 .…”
Section: Discussionmentioning
confidence: 99%