Breast Cancer in South East Asia: Comparison of Presentation and Outcome Between a Middle Income and a High Income Country

Saxena, Nakul; Hartman, Mikael; Bhoo-Pathy, Nirmala; Lim, Jennifer N. W.; Aw, Tar-Ćhing; Iau, Philip; Taib, Nur Aishah Mohd; Lee, Soo‐Chin; Yip, Cheng‐Har; Verkooijen, Helena M.

doi:10.1007/s00268-012-1746-2

Cited by 28 publications

(27 citation statements)

References 48 publications

(45 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The size of invasive tumors can also be used to evaluate disease, and the average sizes in Singapore and Malaysia are 2.2 cm and 3.0 cm, respectively 49. A review evaluating tumor characteristics in Asia and Africa reveals tumors averaging 3.3 cm in Tunisia, and 4.8 cm in Sudan and Nigeria.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Breast cancer screening in developing countries

Vieira¹,

Biller²,

Uemura³

et al. 2017

Clinics

171

100

View full text Add to dashboard Cite

Developing countries have limited healthcare resources and use different strategies to diagnose breast cancer. Most of the population depends on the public healthcare system, which affects the diagnosis of the tumor. Thus, the indicators observed in developed countries cannot be directly compared with those observed in developing countries because the healthcare infrastructures in developing countries are deficient. The aim of this study was to evaluate breast cancer screening strategies and indicators in developing countries.A systematic review and the Population, Intervention, Comparison, Outcomes, Timing, and Setting methodology were performed to identify possible indicators of presentation at diagnosis and the methodologies used in developing countries. We searched PubMed for the terms “Breast Cancer” or “Breast Cancer Screening” and “Developing Country” or “Developing Countries”.In all, 1,149 articles were identified. Of these articles, 45 full articles were selected, which allowed us to identify indicators related to epidemiology, diagnostic intervention (diagnostic strategy, diagnostic infrastructure, percentage of women undergoing mammography), quality of intervention (presentation of symptoms at diagnosis, time to diagnosis, early stage disease), comparisons (trend curves, subpopulations at risk) and survival among different countries.The identification of these indicators will improve the reporting of methodologies used in developing countries and will allow us to evaluate improvements in public health related to breast cancer.

show abstract

Section: Resultsmentioning

confidence: 99%

“…However, differences in tumor size at diagnosis, clinical stage at diagnosis, and treatment were also observed, all of which contributed to a higher survival rate of Singaporean patients 49.…”

Section: Resultsmentioning

confidence: 99%

Breast cancer screening in developing countries

Vieira¹,

Biller²,

Uemura³

et al. 2017

Clinics

171

100

View full text Add to dashboard Cite

show abstract

“…Previous studies indicate that socioeconomic status of the region can influence the diagnosis and treatment of breast cancer which can affect course and prognosis. [4,5,18] Our early single-center study in China's Shaanxi Province showed that the occupation and education of patients with breast cancer had a significant impact on TNM staging, clinical and pathological features, implementation of clinical examination, and the selection of treatment patterns. [9] To further confirm these associations, we conducted this novel multicenter study in which the results confirmed that our previously observed associations also existed across the whole of China.…”

Section: Discussionmentioning

confidence: 99%

Influence of occupation and education level on breast cancer stage at diagnosis, and treatment options in China

et al. 2017

View full text Add to dashboard Cite

The objective of this study was to evaluate the impact of occupation and education level of Chinese female breast cancer patients on their cancer staging at diagnosis, clinical and pathological features, rate of implementation, and selection of treatment.The medical charts of 4211 confirmed female breast cancer cases diagnosed between 1999 and 2008, from 7 breast cancer centers spread across the whole of China, were reviewed. Data including information on the patient's sociodemographic status, clinical and pathological characteristics, implementation of clinical examination and treatment modalities were analyzed. In parallel, the associations between different occupations and level of educational attainment were analyzed in relation to tumor stage through TNM staging, clinical and pathological characteristics, implementation of clinical examination, and treatment patterns. Multivariate logistic regression was used to identify whether the occupation and education level of patients are independent factors of TNM staging at diagnosis.There were significant differences among different occupation groups and the education level of patients in regards to pathological characteristics and treatment choice. Both the occupation and education level of patients were independent factors of TNM staging at diagnosis. For patients within the lower-income occupation or lower educational attainment group, the tumor stage was later, the rates of implementation of relevant investigations were lower, as were the rates of radiotherapy, chemotherapy, and endocrine therapy.This study suggests that strategies should work toward developing more accurate and effective breast cancer prevention and treatment strategies aimed specifically at patients with lower educational attainment levels and at specific occupation groups.

show abstract

“…Compared to Singaporeans, Malaysian women with breast cancer have a significantly lower overall 5‐year survival rate (69% vs 80%), and a 67% increased risk of mortality. This then warrants closer attention to be paid to addressing the issue of CAM use given that it, directly or indirectly, leads to late presentation and inadequate treatment, which have been highlighted as factors which have led to high mortality rates . Moving forward, tighter regulations will not make a significant impact, especially given the fact that CAM use is so deeply entrenched in local culture and beliefs.…”

Section: Discussionmentioning

confidence: 99%

Brief review of complementary and alternative medicine use among Malaysian women with breast cancer

Khan

Jacob

2017

Pharmacy Practice and Res

View full text Add to dashboard Cite

Breast cancer is rated as the most common cancer among women in Malaysia, resulting in 25% of cancer‐related deaths in women. However, effective management has been impeded by the burgeoning use of complementary and alternative medicine (CAM) by these patients. Indeed, women with breast cancer in Malaysia present at a later stage of the disease compared to women from other countries, and a contributing factor has been their preference for CAM treatment prior to seeking conventional therapy. This article explores the impetus behind the use of CAM, and highlights some measures that can be taken to address this issue. Some of the influencing factors noted were patients' lack of knowledge, sociocultural factors, as well as poor communication with healthcare providers. There needs to be a concerted effort by the key players who are either directly or indirectly involved in the care of these patients to address whatever misconceptions they may have that are related to cancer as well as CAM use. Pharmacists especially, as the drug experts, can play a bigger role in educating these patients on the importance of using evidence‐based treatments.

show abstract

Breast Cancer in South East Asia: Comparison of Presentation and Outcome Between a Middle Income and a High Income Country

Abstract: Differences in way of presentation (except stage and tumor size) and treatment of breast cancer patients from the two countries are small. The overall survival of breast cancer patients from Malaysia is much lower than that of Singaporean patients.

Cited by 28 publications

References 48 publications

Breast cancer screening in developing countries

Breast cancer screening in developing countries

Influence of occupation and education level on breast cancer stage at diagnosis, and treatment options in China

Brief review of complementary and alternative medicine use among Malaysian women with breast cancer

Contact Info

Product

Resources

About