Breast cancer in Israel, 1960–1975. II. Effects of age and origin on survival

Melnik, Y.; Slater, Paul E.; Katz, L.M.; Davies, Angela M.

doi:10.1016/0014-2964(80)90247-9

Cited by 13 publications

(4 citation statements)

References 4 publications

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“…At the present time, the precise interrelationship between place of birth, aggressiveness of disease, and the presence of gp52-related antigen is difficult to define because no direct correlation has been made between comparable groups of North-African-and Europeanborn patients. Although North-African-born Israeli breast cancer patients appear to have more aggressive disease than those born in Europe (Melnik et al, 1980), Keydar et al (1982) were unable to divide the entire group of North African patients by clinical stage, and survival data were only available on 5 patients. Similarly, we do not have comparative data on European and Tunisian patients with PEV 0 treated in the same institution (although RPBCPEV has been observed in French Tunisians, all of the patients in this series were native Tunisians except one German woman married to a Tunisian).…”

Section: Discussionmentioning

confidence: 98%

Increased incidence of mouse mammary tumor virus‐related antigen in tunisian patients with breast cancer

Levine

Mesa-Tejada²,

Keydar³

et al. 1984

Intl Journal of Cancer

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Biopsies obtained from 74 Tunisian women with breast cancer (33 cases), benign breast disease (17 cases), and cervical cancer (24 cases) were assayed for the presence of an antigen cross-reacting with gp52 of the mouse mammary tumor virus (MMTV) in order to determine the frequency and possible prognostic significance of this antigen in a form of rapidly progressing breast cancer designated poussée évolutive or PEV. Antigen was detected in 23/33 breast carcinomas (70%) but in none of the 41 control specimens. An evaluation of reactivity according to tumor aggressiveness and survival could be performed in retrospect on 29 of the breast cancer patients with a follow-up of up to 11 years. The frequency of gp52-related antigen was similar in the patients with the most aggressive form of PEV with inflammatory signs (8/12 or 67% positive) and those breast cancer patients without PEV (12/17 or 71% positive). Within each of the two groups, PEV+ and PEV 0, no correlation was observed between the presence or absence of antigen and the disease-free interval or survival. We conclude that the identification of gp52-related antigens in the breast cancer biopsies from North African women has implications different from those observed in other populations. While thus far not indicative of disease aggressiveness and prognosis, the higher frequency of detectable antigen in comparison to biopsies obtained from patients born in the United States and Europe may have relevance to the etiology and pathogenesis of the disease.

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Section: Discussionmentioning

confidence: 98%

Increased incidence of mouse mammary tumor virus‐related antigen in tunisian patients with breast cancer

Levine

Mesa-Tejada²,

Keydar³

et al. 1984

Intl Journal of Cancer

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“…Corresponding times at these Stages reported from elsewhere are-Israel 4.2 and 1.2 years (Melnick et al, 1980); and in Cambridge, UK, about 4 and I years (estimated from Figure 7, Haybittle, 1979). In a study made in Chicago, for Stage III patients, 50% had died by 3-3k years (Ferguson et al, 1982).…”

mentioning

confidence: 75%

“…Before our initiation of a prospective investigation, it was thought that it would be of value to carry out a retrospective study. The need for survival information in the context described has been stimulated in part by current interest in survival times from breast cancer in Western populations, as affected by age, staging, oestrogen receptor capacity, obesity, ethnic group and other variables (Mueller et al, 1975(Mueller et al, , 1978Haybittle 1979;Wilkinson et al, 1979;Langlands et al, 1979;Melnick et al, 1980;Brian et al, 1980;Nagpal et al, 1980;Chen & Asal, 1980;Ferguson et al, 1982;Paterson et al, 1982;Bonett & Roder, 1982;Hibberd et al, 1983;Mason et al, 1983).…”

mentioning

confidence: 99%

Low survival of South African urban black women with breast cancer

Walker¹,

Walker²,

Tshabalala³

et al. 1984

Br J Cancer

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“…Melnik et al (9) studied 10,702 breast cancer patients diagnosed in Israel over 16 years (1960-1975). Although they found no difference in survival between older and younger women (50% died at the time of their study; cause of death was known in 82% of the patients), death from breast cancer fell with advancing age and death from other causes increased.…”

Section: Statistical Outcome Of Patients With Breast Cancermentioning

confidence: 99%

Patterns of metastasis and natural courses of breast carcinoma

Lee

1985

Cancer Metast Rev

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Breast carcinoma is known to metastatize to all organs. In order to understand the patterns of spread and natural courses, this review summarizes detailed studies of patients with various stages of the disease. After treatment of early breast carcinoma (stage I, II, and some III), the recurrent lesion can be classified as local, regional, distant, or combinations thereof. The sites of dissemination of patients presenting with stage IV disease and of those who had autopsy after diagnosis of breast cancer are presented for comparison. Clinicopathological factors that influence the relative incidence, specific site, subsequent event, and prognosis of recurrent and metastatic breast cancers are discussed.

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Breast cancer in Israel, 1960–1975. II. Effects of age and origin on survival

Cited by 13 publications

References 4 publications

Increased incidence of mouse mammary tumor virus‐related antigen in tunisian patients with breast cancer

Increased incidence of mouse mammary tumor virus‐related antigen in tunisian patients with breast cancer

Low survival of South African urban black women with breast cancer

Patterns of metastasis and natural courses of breast carcinoma

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