Breast cancer in adolescents and young women

Shannon, Catherine; Smith, Ian

doi:10.1016/s0959-8049(03)00669-5

Cited by 151 publications

(128 citation statements)

References 83 publications

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“…Other risk factors for local recurrence after BCT in all age groups were infiltrating tumour with an extensive intraductal component, vascular invasion and involvement of excision margins. 13 Conservative surgery without radiotherapy was shown in various studies to have higher local recurrence rates in women with early onset cancer. 18 In the EORTC (European Organisation for Research and Treatment fo Cancer) "boost versus no boost" randomised trial, local failure rate was reduced from 20% to 10% in patients < 40 years of age, a more pronounced result compared with patients > 50 years.…”

Section: Breast Cancer Incidence Rates In Africa As a Developing Contmentioning

confidence: 99%

“…In the United States, 2.7 % of patients with breast cancer are younger than 35 years. 13 It is reported that in the United States the incidence in women 20-24 years of age is 1.4 per 100,000 women, and for women aged 25-29 years 8.1 per 100,000 women. In women between the ages of 30-34 years, the incidence increases to 24.8 per 100,000 women.…”

Section: Introductionmentioning

confidence: 99%

“…In women between the ages of 30-34 years, the incidence increases to 24.8 per 100,000 women. 13 Although a relatively rare disease in young women, a diagnosis of breast cancer impacts severely on the young patient's life and future, extending to her family and society as a whole. It also impacts on the medical personnel involved in her treatment and care giving.…”

Section: Introductionmentioning

confidence: 99%

“…It has been shown that in young women, breast cancer has more aggressive biological features 1,6 with more advanced disease at diagnosis 13 and a poorer prognosis (especially in the < 30 years age group) than older premenopausal patients. 13 Much research still needs to be done on various aspects of breast cancer in this young population.…”

Section: Introductionmentioning

confidence: 99%

“…13 Much research still needs to be done on various aspects of breast cancer in this young population. Interesting topics arise, such as the contribution of BRCA 1 and 2 germ line mutations in this young population, as well as other genetic influences and factors.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Young breast cancer patients in the developing world: incidence, choice of surgical treatment and genetic factors

Krüger¹,

Apffelstaedt

2007

South African Family Practice

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Section: Breast Cancer Incidence Rates In Africa As a Developing Contmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Young breast cancer patients in the developing world: incidence, choice of surgical treatment and genetic factors

Krüger¹,

Apffelstaedt

2007

South African Family Practice

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Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response

Chanan‐Khan

Miller

Lawrence

et al. 2010

Cancer

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Age standardized incidence rates of breast cancer in developed countries is nearly threefold higher than in developing countries. Iran has had one of the lowest incidence rates for breast cancer in the world, but during the last four decades increasing incidence rates of breast cancer made it the most prevalent cancer in Iranian women. After adjustment for age, Iranian young women are at relatively higher risk of breast cancer than their counterparts in developed countries. The purpose of this study was to investigate some established risk factors of breast cancer in Iranian young women. A hospital‐based case control study comprising 521 women with histologically confirmed, incident breast cancer and 521 controls frequency‐matched by age and province of residence was conducted. Logistic regression performed to investigate associations of reproductive and anthropometric factors with breast cancer risk. In multivariate analysis, family history [odds ratio (OR): 1.61; 95% confidence interval (CI): 1.07–2.42], oral contraceptives (OC) usage (OR: 1.52; 95% CI: 1.11–2.08), low parity (OR parity ≥ 3 vs. 1–2: 0.33; 95% CI: 0.23–0.49), employment (OR: 1.83; 95% CI: 1.05–3.23) and shorter period of breast feeding (OR ≥ 37 months vs. < 37: 0.61; 95% CI: 0.44–0.84) were related to a higher risk of breast cancer in young women. This was the first study focusing on risk factors of breast cancer in Iranian young women. The trend of decreasing parity and shortened duration of breast feeding along with OC usage might partly explain the rapid rising of breast cancer incidence in Iranian young women.

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Risk factors for breast cancer among young women in southern Iran

Ghiasvand

Maram

Tahmasebi

et al. 2010

Intl Journal of Cancer

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Age standardized incidence rates of breast cancer in developed countries is nearly threefold higher than in developing countries. Iran has had one of the lowest incidence rates for breast cancer in the world, but during the last four decades increasing incidence rates of breast cancer made it the most prevalent cancer in Iranian women. After adjustment for age, Iranian young women are at relatively higher risk of breast cancer than their counterparts in developed countries. The purpose of this study was to investigate some established risk factors of breast cancer in Iranian young women. A hospitalbased case control study comprising 521 women with histologically confirmed, incident breast cancer and 521 controls frequency-matched by age and province of residence was conducted. Logistic regression performed to investigate associations of reproductive and anthropometric factors with breast cancer risk. In multivariate analysis, family history [odds ratio (OR): 1.61; 95% confidence interval (CI): 1.07-2.42], oral contraceptives (OC) usage (OR: 1.52; 95% CI: 1.11-2.08), low parity (OR parity ! 3 vs. 1-2: 0.33; 95% CI: 0.23-0.49), employment (OR: 1.83; 95% CI: 1.05-3.23) and shorter period of breast feeding (OR ! 37 months vs. < 37: 0.61; 95% CI: 0.44-0.84) were related to a higher risk of breast cancer in young women. This was the first study focusing on risk factors of breast cancer in Iranian young women. The trend of decreasing parity and shortened duration of breast feeding along with OC usage might partly explain the rapid rising of breast cancer incidence in Iranian young women.Breast cancer is the second most prevalent cancer in the world and the most common cancer among women. Breast cancer still persists as an international health burden despite advances in its early diagnosis, treatment and also increased knowledge of its established risk factors.

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Breast cancer in adolescents and young women

Cited by 151 publications

References 83 publications

Young breast cancer patients in the developing world: incidence, choice of surgical treatment and genetic factors

Young breast cancer patients in the developing world: incidence, choice of surgical treatment and genetic factors

Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response

Risk factors for breast cancer among young women in southern Iran

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