volume 345, issue 3, P159-164 2001
DOI: 10.1056/nejm200107193450301
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Hanne Meijers-Heijboer, Bert van Geel, Wim L.J. van Putten, Sonja C. Henzen-Logmans, Caroline Seynaeve, Marian B.E. Menke-Pluymers, Carina C.M. Bartels, Leon C. Verhoog, Ans M.W. van den Ouweland, Martinus F. Niermeijer, Cecile T.M. Brekelmans, Jan G.M. Klijn

Abstract: In women with a BRCA1 or BRCA2 mutation, prophylactic bilateral total mastectomy reduces the incidence of breast cancer at three years of follow-up.