Breast Cancer: A Review of Mammography and Clinical Breast Examination for Early Detection of Cancer

Balali, Gadafi Iddrisu; Yar, Denis Dekugmen; Dela, Vera Gobe Afua; Effah-Yeboah, Emmanuel; Asumang, Philip; Akoto, Justice Delali; Abdallah, Fuseini

doi:10.4236/oalib.1106866

Cited by 4 publications

(1 citation statement)

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“…BC is the female cancer with the highest morbidity rate worldwide, and at present, there is no radical treatment for metastasis [ 48 ]. BC is a frequently occurring cancer in females and a major reason leading to mortality; approximately 508,000 women die annually from BC [ 49 ]. In developed countries, BC has a generally favorable prognosis, but the situation in developing countries is not favorable, and locally advanced BC is reported to be associated with a high morbidity rate [ 50 ].…”

Section: Introductionmentioning

confidence: 99%

High temperature requirement A1 in cancer: biomarker and therapeutic target

Chen

Yang

et al. 2021

Cancer Cell Int

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As the life expectancy of the population increases worldwide, cancer is becoming a substantial public health problem. Considering its recurrence and mortality rates, most cancer cases are difficult to cure. In recent decades, a large number of studies have been carried out on different cancer types; unfortunately, tumor incidence and mortality have not been effectively improved. At present, early diagnostic biomarkers and accurate therapeutic strategies for cancer are lacking. High temperature requirement A1 (HtrA1) is a trypsin-fold serine protease that is also a chymotrypsin-like protease family member originally discovered in bacteria and later discovered in mammalian systems. HtrA1 gene expression is decreased in diverse cancers, and it may play a role as a tumor suppressor for promoting the death of tumor cells. This work aimed to examine the role of HtrA1 as a cell type-specific diagnostic biomarker or as an internal and external regulatory factor of diverse cancers. The findings of this study will facilitate the development of HtrA1 as a therapeutic target.

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Section: Introductionmentioning

confidence: 99%