Breast augmentation: Part II – adverse capsular contracture

Berry, Miles G.; Cucchiara, Vito; Davies, David G.

doi:10.1016/j.bjps.2010.04.011

Cited by 68 publications

(55 citation statements)

References 93 publications

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“…Mastectomy flap surgery has good cosmetic out-comes for patients with larger tumors (the resection ration ≥ 1/5) compared to the method conserving smaller breasts. In addition, the breasts' symmetry should be considered; however, there is a disagreement regarding the restoration time to maintain symmetry in breasts (17)(18)(19)(20)(21). Considering the 0.1% to 5% probability of the metastasis to the opposite breast and also significant decrease in the level of breast cancer incidence in females over 50 years due to reduction in breast size may reduce the possibility of cancer incidence (22)(23)(24)(25)(26).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Surgical Margin After Breast Cancer Surgery Between Oncoplastic Technique and Conventional Breast-Conserving Surgery

et al. 2018

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Background: Compared to other breast surgery methods, the accurate determination of pathologic margin in oncoplastic technique can affect its development and further employment of this technique. The current study aimed at evaluating positive pathologic margin after oncoplastic surgery and comparing it to that of the conventional breast-conserving surgery. Methods: The current cross sectional and prospective study enrolled patients with breast cancer referring to the surgical clinic of Tehran Cancer Institute from 2010 to 2013. In this study, patients with breast cancer were evaluated based on the type of surgery (oncoplastic or conventional breast-conserving) they had undergone. Accordingly, the positive or negative result of the margin surgery was compared between the groups. Results: In the current study, 317 patients with breast cancer underwent the surgery during the study period (154 patients in the oncoplastic and 163 patients in the conventional breast-conserving surgery groups). The highest frequency in the oncoplastic surgery belonged to Omega method (27.3%). The pathological evaluations after surgery showed ductal breast carcinoma in most of the cases in both groups (oncoplastic surgery = 94.2%; conventional breast-conserving surgery = 90.8%; P = 0.053). Positive margin in oncoplastic surgery and conventional breast-conserving surgery groups were 10.4% and 18.4%, respectively (P = 0.043). Among the 317 studied subjects, 14 relapse cases were observed; in 7 cases, mastectomy and in the rest, re-excision were conducted. Two out of 14 cases belonged to the positive margin group. Conclusions: Using oncoplastic surgery as a method for breast surgery may play an important role in reducing the prevalence of positive margins compared to the conventional breast-conserving surgery.

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Section: Introductionmentioning

confidence: 99%

Comparison of Surgical Margin After Breast Cancer Surgery Between Oncoplastic Technique and Conventional Breast-Conserving Surgery

et al. 2018

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“…Like all nonabsorbable implants, silicone may cause fibrous capsule formation of varying thickness. 18,19 Myofibroblasts are contractile fibroblasts found in fibrous capsule, which provide a contractile force and decrease the surface area of the capsule, leading to the capsule contracture over time. 20 Moreover, clinical study of capsular contractures after aesthetic breast augmentation revealed that the average tensile strength of the capsule was 44±38 N, 21 and the intracapsular pressure correlated positively with the degree of capsule thickness.…”

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confidence: 99%

Polycaprolactone nanofibrous mesh reduces foreign body reaction and induces adipose flap expansion in tissue engineering chamber

Luo¹,

He²,

Chang³

et al. 2016

IJN

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“…Severe fibrotic reaction to foreign body such as silicone implant is an important cause of capsular contracture [13]. In addition, the stage of capsular fibrosis after breast augmentation is one of the main indicators of the severity of BCC [14]. TGF-β is a multifunctional cytokine that play a central role in tissue repair and fibrosis, which stimulates the production of various extracellular matrix proteins and inhibits the degradation of these matrix proteins [15].…”

Section: Discussionmentioning

confidence: 99%

Cross-Linked Hyaluronic acid can Prevent the Capsular Contracture Formation

Chou¹,

Hsu²,

Hsu³

et al. 2017

Gen Med

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Introduction: Breast reconstruction using silicone implants is a widespread choice, however, breast capsular contracture (BCC), a response of the immune system to foreign materials, is the most affliction and frustration fibrosis complications after silicone implantation. Chronic inflammation-associated fibrosis is regarded as a main cause of BCC. Hyaluronic acid (HA) is an effective anti-adhesive and anti-fibrotic agent. Furthermore, 1,4-butanediol diglycidyl ether-cross-linked hyaluronan hydrogel (cHA) is a non-resorbable cross-linked hyaluronan-derived polymer with no cytotoxicity and high stability. This study aims to evaluate the potential of cHA on preventing BCC in breast surgery using silicone implants.

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Breast augmentation: Part II – adverse capsular contracture

Cited by 68 publications

References 93 publications

Comparison of Surgical Margin After Breast Cancer Surgery Between Oncoplastic Technique and Conventional Breast-Conserving Surgery

Comparison of Surgical Margin After Breast Cancer Surgery Between Oncoplastic Technique and Conventional Breast-Conserving Surgery

Polycaprolactone nanofibrous mesh reduces foreign body reaction and induces adipose flap expansion in tissue engineering chamber

Cross-Linked Hyaluronic acid can Prevent the Capsular Contracture Formation

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