Breaking-up sedentary time is associated with impairment in activities of daily living

Abstract

This file was dowloaded from the institutional repository Brage NIH -brage.bibsys.no/nih Sardinha, L. B., Ekelund, U., dos Santos, L., Cyrino, E. S., Silva, A. M., Santos, D. (2015). AbstractIdentifying modifiable behaviours associated with prevention of activities of daily living (ADL) impairments is vital to implement preventive strategies for independent living in elderly. We aimed to examine the associations between objectively measured breaks in sedentary time with ADL impairments and physical independence. Cross-sectional assessments were carried out in 371 participants (131 male) aged 65-103 years from the Portuguese surveillance system of physical activity. Physical Activity (PA) and sedentary time (ST) were assessed with accelerometry, and ADL impairments and physical independence with the self-reported 12-item composite physical function scale. Using ROC analyses a cut-off of 7 hourly breaks in sedentary time was identified which maximized the sensitivity and specificity in diagnosing physical dependence. Logistic regression analysis demonstrated that, independently of moderate-to-vigorous PA (MVPA), participants performing ≤7 hourly breaks in sedentary time had 2 to 7 fold increased odds for impairment in 10 of the 12 ADL. When stratifying ADL into basic, instrumental and advanced ADL we verified that less than 7 hourly breaks in sedentary time was associated (p<0.05) with a 2 to 5 fold increased odds for impairments and physical dependence, independent of MVPA. No associations (p>0.05) were observed between meeting PA guidelines and basic, instrumental, and advanced ADL impairment although time in MVPA was lower (p<0.05) in participants showing impairments. In conclusion, the frequency of breaks in sedentary time in older ages is independently associated with lower risk for ADL impairments and physical dependence. Our findings support interventions to encourage older adults to increase overall PA by interrupting sedentary time.

Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity

“…Still, current results diverge from those observed among such studies of non-RA populations, in which sedentary behaviour (≤1.5 METs) and LPA (1.6–2.9 METS) are reported to be related to CVD risk profile and physical function [22–24, 36–40, 43, 46, 47, 64]. The absence of significant relationships in the current study, may therefore be due in part to the disproportionately higher levels of inflammation observed in RA, relative to other populations.…”

“…With regards to examination of the relationships between sedentary time, sedentary behaviour patterns and LPA with 1) individual CVD risk factors and 2) functional disability, the lack of significant associations reported herein are inconsistent with findings from extant research [22–24, 36–40, 43, 46, 47, 64]. Only the number of sedentary bouts/day  ≥ 20 min was significantly related to secondary outcomes (i.e., positive associations with fibrinogen and ESR).…”

Factors Associated with Sedentary Behavior in Patients with Intermittent Claudication

“…This information is clinically relevant to exercise professionals or surgeons who rehabilitate patients with intermittent claudication because it identifies patients who need more attention with interventions designed to reduce time spent in sedentary activities. Thus, in addition to stimulate increases in physical activity levels, it is also important to recommend breaks in the sedentary behavior, as it have been associated with lower functional impairment 37 .…”

Reducing Sedentary Time among Older Adults in Assisted Living: Perceptions, Barriers, and Motivators

“…Recent reviews have identified an association between time spent sedentary and several important health outcomes that are particularly relevant to older adults, including functional impairments and reduced mobility [11]. In addition to the total time spent sedentary, the pattern of sedentary time may also be important, as more breaks in sedentary time have been associated with better physical function and cardiorespiratory fitness [12,13]. Therefore, simply breaking up sedentary time with short bouts of standing and light-intensity physical activity could be beneficial to health and function [14].…”