Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
Matthew Snelson,
Tim Vanuytsel,
Francine Z. Marques
Abstract:Purpose of the Review
To review what intestinal permeability is and how it is measured, and to summarise the current evidence linking altered intestinal permeability with the development of hypertension.
Recent Findings
Increased gastrointestinal permeability, directly measured in vivo, has been demonstrated in experimental and genetic animal models of hypertension. This is consistent with the passage of microbial substances to the systemic circulation and… Show more
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