Brazilian Ginseng extraction via LPSE and SFE: Global yields, extraction kinetics, chemical composition and antioxidant activity

New proposal for production of bioactive compounds by supercritical technology integrated to a sugarcane biorefinery

“…No thermal benefits could be accounted for the integration of the SFE plant to the sugarcane biorefinery producing first and second generation ethanol, but difference at the economic potential could be observed considering different raw-material cost and leftover extracted material price. Leal et al (2010); b experimental data of the present study. Albarelli et al (2013), c Santos et al 2012b, d (dddd), e (DDD), * ethanol production cost calculated by the simulation % Legend: I -extraction system based in experimental data from Leal et al (2010); II --extraction system based in experimental data of the present study; A -stand-alone extraction system with shared cogeneration with a sugarcane mill; B -extraction system integrated with a sugarcane mill.…”

“…In this context, supercritical fluid extraction (SFE) process has been successfully applied for different bioactive compounds sources, including Pfaffia glomerata roots. Leal et al (2010) obtained an extract employing CO2+ethanol (90:10 %, w/w) at 20 MPa and 303 K as extracting solvent with a concentration of up to 3.7 % for β-ecdysone (which is 3.8-fold higher to the concentration in the commercial extracts), which indicates the possible use of those extracts directly in the commercial pharmaceutical products. Based on these findings, this work first aims the optimization of β-ecdysone recovery by SFE.…”

“…The operational conditions used in each step, as well as the extraction yield and β-ecdysone content in the extract, are shown in Table 1. It was considered the operation of the system under the conditions experimentally studied by Leal et al (2010) and under the conditions obtained experimentally and discussed at the present paper.…”

“…CO2/ethanol proportion ratio was very significantly (p < 0.01; p = 0.00008) for this response variable, while temperature and pressure showed no influence (p = 0.212719 and p = 0.378168, respectively). Leal et al (2010), studying the SFE from Pfaffia glomerata roots using pure CO2, observed that pressure had different influences on the extraction process at different temperatures. During SFE using CO2 without any cosolvent, the effect of temperature and pressure on supercritical CO2 solubilization power depends on the solute vapor pressure and solvent density, being the extraction process strongly affected by the CO2 density.…”

Multi-objective Optimization of Supercritical Water Gasification of Leftover Brazilian Ginseng Roots After Phytochemical Recovery Steps

“…In addition, other important compounds have been identified and could be also recovered with a subsequent extraction process. Our research group has demonstrated that pressurized ethanol, with or without the addition of CO 2 , can successfully be applied as solvent for extracting selectively β-ecdysone from P. glomerata roots (Leal et al, 2010;Santos et al, 2014). On the other hand, a recent patent developed by us described that water can be used as extracting solvent for obtaining a saponin-rich extract that can be used directly as surfactant (Meireles et al, 2013).…”