Branching ratio and γ-ray emission probabilities in the decay of the Jπ=13<

Towards the Stable Binding of Mercury: Synthesis and Functionalization of Dibenzyldiazabicyclononane Scaffolds

“…The Auger electron emissions per decay have energies similar to those of 125 I, which has already been shown to be effective in inducing cell death by extracellular irradiation. [19][20][21] With physical half-lives of 23.82 h ( 197m Hg) and 64.81 h ( 197 Hg) [22] as well as the single stable decay product 197 Au, the innate radioisotope pair 197(m) Hg fulfills the concept of radionuclide theranostics and holds promise for future radiopharmaceutical applications in nuclear medicine. [17,23] Interest in mercury in modern chemistry is rather low, primarily due to its toxicity.…”

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

“… [5] The high number of Auger electron (AE) emissions per decay ( 197m Hg: 19, 197 Hg: 23) also have great therapeutic potential, with similar energies to 125 I, which has already shown that even extracellular AE radiotherapy can effectively cause cell death. [ 6 , 7 , 8 ] Combined with the practical half‐lives of 23.82 h and 64.81 h (for the metastable and ground state nuclear isomers respectively) [9] and the stable 197 Au decay product, the innately theranostic nuclide 197(m) Hg is a promising candidate for radiopharmacy. [ 10 , 11 ]…”

“…[5] The high number of Auger electron (AE) emissions per decay ( 197m Hg: 19,197 Hg: 23) also have great therapeutic potential, with similar energies to 125 I, which has already shown that even extracellular AE radiotherapy can effectively cause cell death. [6][7][8] Combined with the practical half-lives of 23.82 h and 64.81 h (for the metastable and ground state nuclear isomers respectively) [9] and the stable 197 Au decay product, the innately theranostic nuclide 197(m) Hg is a promising candidate for radiopharmacy. [10,11] There is historical precedence for the medicinal use of radiomercury, as during the 1960s and early 1970s reactor produced 197 Hg with low specific activity did see clinical use in diagnostics, for kidney and brain imaging, in the radiolabelled chlormerodrin, [12] a mercurial diuretic commercially traded from 1952 [13] till 1974.…”