Branched chain amino acids alter fatty acid profile in colostrum of sows fed a high fat diet

Abstract

Background: Branched chain amino acids (BCAAs) are important substrates for milk protein synthesis in the mammary gland, and are tightly related to lipid metabolism. No study has been performed examining the role of BCAAs with high fat diets on milk fat synthesis. This study was designed to investigate the effect of dietary BCAAs on growth performance of piglets, progeny body weight, and milk fat composition in sows fed a high fat diet. Four diets (CON = control diet; HF = high fat diet with 8% soybean oil; HF-MB=HF plus 0.39% BCAAs; HF-HB=HF plus 0.78% BCAAs) were fed to sows from late gestation to weaning. Results: Compared to HF, BCAAs (HF-MB and HF-HB) increased the litter weight (P < 0.05) and overall litter weight gain (P < 0.05) at weaning and increased colostrum fat content by 27.3-35.8% (P < 0.01). Fatty acid profiles between the two doses of BCAAs were similar. Compared with HF, HF-MB tended to decrease the percentage of C18:3n3 (P = 0.063) and increased the percentage of C18:1n9c (P = 0.03). In addition, BCAAs in HF-MB increased the concentration of total fatty acid by 22.1% in colostrum (P = 0.03) but decreased that in serum at parturition by 53.2% (P = 0.027). The fatty acids in colostrum that increased with BCAAs were C15:

Supplementation alpha glycerol monolaurate during late gestation and lactation enhanced sow performance, ameliorated milk composition, and improved growth of suckling piglets

“…However, this study is the rst one using α-GML for sow nutrition. We found that dietary α-GML inhibited de novo lipogenesis of the mammary gland (lower percentage of the sum of C8:0, C10:0, C12:0, and C14:0 in milk), which consistent with published studies in sows [33]. Consistent with the experimental diet treatment, C12:0 in colostrum and milk was higher from sows-fed α-GML than the control sows.…”

Cooperative Interaction of Phenolic Acids and Flavonoids Contained in Activated Charcoal with Herb Extracts, Involving Cholesterol, Bile Acid, and FXR/PXR Activation in Broilers Fed with Mycotoxin-Containing Diets

“…We measured very low concentrations of fatty acids (4.5 μg per mg of CHC, Table S2 , refs. [ 81 , 82 , 83 ]) in CHC. With such low concentrations of fatty acids, we could not perform the treatment of primary cells.…”

Understanding Nutrition and Metabolism of Threatened, Data-Poor Rheophilic Fishes in Context of Riverine Stocking Success- Barbel as a Model for Major European Drainages?

“…Branched-chain AAs (BCAAs; such as isoleucine, valine), besides their recently asserted role in glucose metabolism [ 94 , 95 ], are also linked with fatty acids metabolism. Recent evidence suggests catabolism of these BCAAs contributes to odd chain and long-chain FAs synthesis [ 96 , 97 , 98 ]. The presently observed negative correlation between BCAAs and some FAs in rheophilic cyprinids body (barbel, nase, asp and vimba bream; Figure 3 ) is interesting.…”